Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study

In Argentina, circulation of hepatitis E virus (HEV) genotype 3 has been described, producing sporadic cases of acute and chronic hepatitis. Limited information is available regarding HEV infection in children, so we aimed to investigate this virus in a pediatric population from the country. Serum samples from Argentine children (0–18 years old) (n = 213) were studied for IgG anti-HEV, IgM anti-HEV and RNA-HEV: 202 samples belonged to individuals attending health-care centers for routine check-ups, and 11 samples from patients with acute hepatitis of unknown etiology. Seropositivity for IgG anti-HEV was 1.49 % (3/202). One sample from an 18-years-old female patient with acute hepatitis tested positive for IgM anti-HEV detection, negative for IgG anti-HEV and RNA-HEV, but also positive for IgM anti-EBV. The HEV prevalence was low and showed circulation among children in central Argentina.

Palabras clave: HEV , ARGENTINA , CHILDREN , INFECTION , COINFECTION

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Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution 2.5 Unported (CC BY 2.5)

Identificadores

URI: http://hdl.handle.net/11336/238607

URL: https://linkinghub.elsevier.com/retrieve/pii/S2405844024083154

DOI: http://dx.doi.org/10.1016/j.heliyon.2024.e32284

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Articulos(CCT - CORDOBA)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - CORDOBA

Citación

Cervella, Lorena L.; García Oro, Cecilia; Fantilli, Anabella Clara; Di Cola Bucciarelli, Guadalupe; Martínez Wassaf, Maribel G.; et al.; Hepatitis E virus in children and adolescents living in an urban environment in central Argentina: An explorative study; Elsevier; Heliyon; 10; 11; 6-2024; 1-6

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