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dc.contributor.author
Barrientos, Gabriela Laura
dc.contributor.author
Ronchi, Francesca
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Conrad, Melanie L.
dc.date.available
2024-06-03T10:47:59Z
dc.date.issued
2023-12
dc.identifier.citation
Barrientos, Gabriela Laura; Ronchi, Francesca; Conrad, Melanie L.; Nutrition during pregnancy: Influence on the gut microbiome and fetal development; John Wiley & Sons; American Journal of Reproductive Immunology; 91; 1; 12-2023; 1-11
dc.identifier.issn
1600-0897
dc.identifier.uri
http://hdl.handle.net/11336/236769
dc.description.abstract
Pregnancy is a finely tuned process, with the health and well-being of the developing fetus determined by the metabolic status and dietary intake of the mother. The maternal gut microbiome is remodeled during pregnancy, and this, coupled with the maternal nutrient intake during gestation shapes the production of metabolites that can cross the placenta and affect fetal development. As posited by the Developmental Origins of Health and Disease Hypothesis, such environmental influences can have major effects on the developing organ systems. When occurring at particularly sensitive gestational time points, these developmental programming events can have long lasting effects on offspring adaptation to the postnatal environment, and major health implications later in life. This review will summarize current knowledge on how pregnancy and maternal dietary intake intrinsically and extrinsically modify maternal gut microbiota composition and metabolite production. Further, we will assess how these factors shape the fetal landscape and ultimately contribute to offspring health.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
John Wiley & Sons
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.subject
DOHAD
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FETAL DEVELOPMENT
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NUTRITION
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PREGNANCY
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METABOLITES
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MICROBIOME
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SHORT-CHAIN FATTY ACID
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Inmunología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Nutrition during pregnancy: Influence on the gut microbiome and fetal development
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-05-22T11:38:30Z
dc.journal.volume
91
dc.journal.number
1
dc.journal.pagination
1-11
dc.journal.pais
Dinamarca
dc.journal.ciudad
Copenhague
dc.description.fil
Fil: Barrientos, Gabriela Laura. Hospital Aleman. Laboratorio de Medicina Experimental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Ronchi, Francesca. Freie Universität Berlin; Alemania
dc.description.fil
Fil: Conrad, Melanie L.. Freie Universität Berlin; Alemania
dc.journal.title
American Journal of Reproductive Immunology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/aji.13802
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