Artículo
Circulating tumor cells in cancer-risk populations as a cancer interception tool
Serrano, Maria Jose; Christian, Rolfo; Expósito Hernandez, José; Garrido Navas, Carmen; Lopez Hidalgo, Javier; Denninghoff, Valeria Cecilia
Fecha de publicación:
05/2023
Editorial:
Elsevier
Revista:
International Review of Cell and Molecular Biology
e-ISSN:
1937-6448
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Cancer interception (CI) is a new approach to cancer prevention and treatment in a cancer-risk population that aims to detect and treat pre-tumoral stages. It has several potential advantages over traditional cancer diagnosis and monitoring methods because it is non-invasive, making it less painful and risky than conventional biopsy procedures. The circulating tumor cells (CTCs), liquid biopsy family members, are essential for the CI approach; then, the liquid biopsy (LB) is used as a CI tool. LB can be performed frequently because of its easy sampling and early pathological stages, which allow repeated non-invasive monitoring of cancer progression and response to treatment. CTCs have been found in the bloodstream of several types of cancer patients, including in early-stage cancer and premalignant lesions, suggesting a tumor development role in cancer's early stages. This chapter will present foundational scientific studies addressing CI and the clinical impact of CTC screening in a population at risk for cancer.
Palabras clave:
Circulating tumor cells
,
Cancer interception
,
Liquid biopsy
,
Risk population
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Articulos de SEDE CENTRAL
Citación
Serrano, Maria Jose; Christian, Rolfo; Expósito Hernandez, José; Garrido Navas, Carmen; Lopez Hidalgo, Javier; et al.; Circulating tumor cells in cancer-risk populations as a cancer interception tool; Elsevier; International Review of Cell and Molecular Biology; 381; 5-2023; 113-129
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