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dc.contributor.author
Cancela, María Belen
dc.contributor.author
Dinardi, Milagros
dc.contributor.author
Aschero, María del Rosario
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Zugbi, Santiago
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Chantada, Guillermo Luis
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dc.contributor.author
Baroni, Lorena
dc.contributor.author
Schaiquevich, Paula Susana
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dc.date.available
2024-05-22T10:29:05Z
dc.date.issued
2024-05
dc.identifier.citation
Cancela, María Belen; Dinardi, Milagros; Aschero, María del Rosario; Zugbi, Santiago; Chantada, Guillermo Luis; et al.; The importance of basic and translational research in caring for children with malignant solid tumors in Latin America; Organización Panamericana de la Salud; Revista Panamericana de Salud Pública; 48; 5-2024; 1-12
dc.identifier.issn
1020-4989
dc.identifier.uri
http://hdl.handle.net/11336/235791
dc.description.abstract
Objective: Basic and translational research in pediatric cancer are essential to improve patient care. To critically assess the developments achieved in these areas in Latin America, we systematically reviewed information published between 2013 and 2023.Methods: Studies of basic and translational research performed by investigators in Latin America evaluating pediatric malignant solid and central nervous system tumors were retrieved from PubMed. Original articles published in English between 2013 and 2023 were included. Collaborations among Latin American authors or among Latin American authors working with researchers from other continents were also included. Studies were excluded if they focused only on adults or on basic research in tumor biology not specifically related to the tumor types analyzed in this review.Results: A total of 550 articles were retrieved, but after removal of duplicates, 514 articles were included in the analysis, the majority of which were authored by researchers affiliated with institutions in Argentina, Brazil and Mexico. These countries also had the highest number of collaborations on original articles published with authors from Europe and North America. Argentina had the highest number of collaborations on original publications, with coauthors from Brazil and Uruguay. The median impact factor of the 244 journals in which articles were published was 3.5. The most commonly studied tumors were osteosarcomas, neuroblastomas and medulloblastomas; the most commonly studied areas were molecular analysis, tumor cell biology and biomarkers.Conclusions: In Latin America, research in pediatric oncology is on the agenda, despite a notable disparity in publication rates and frequency of collaboration between countries. There is a need to strengthen scientific collaboration within Latin America and with countries from other continents to promote research and to develop novel treatment strategies that reflect the local needs of children in Latin America who have solid tumors and brain cancer.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Organización Panamericana de la Salud
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
LATIN AMERICA
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PEDIATRIC
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ONCOLOGY
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BRAIN NEOPLASM
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Otras Medicina Básica
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
The importance of basic and translational research in caring for children with malignant solid tumors in Latin America
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-05-16T12:40:37Z
dc.journal.volume
48
dc.journal.pagination
1-12
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Cancela, María Belen. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
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Fil: Dinardi, Milagros. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
dc.description.fil
Fil: Aschero, María del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina. Hospital Sant Joan de Deu Barcelona; España
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Fil: Zugbi, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
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Fil: Chantada, Guillermo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina. Hospital Sant Joan de Deu Barcelona; España
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Fil: Baroni, Lorena. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
dc.description.fil
Fil: Schaiquevich, Paula Susana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Gobierno de la Ciudad de Buenos Aires. Hospital de Pediatría "Juan P. Garrahan"; Argentina
dc.journal.title
Revista Panamericana de Salud Pública
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://iris.paho.org/handle/10665.2/59522
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.26633/RPSP.2024.48
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