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dc.contributor.author
Brusca, María Isabel
dc.contributor.author
Irastorza, Ramiro Miguel
dc.contributor.author
Cattoni, Diego Ignacio
dc.contributor.author
Ozu, Marcelo
dc.contributor.author
Chara, Osvaldo
dc.date.available
2017-09-04T17:28:33Z
dc.date.issued
2013-05
dc.identifier.citation
Brusca, María Isabel; Irastorza, Ramiro Miguel; Cattoni, Diego Ignacio; Ozu, Marcelo; Chara, Osvaldo; Mechanisms of interaction between Candida albicans and Streptococcus mutans: An experimental and mathematical modelling study; Taylor & Francis; Acta Odontologica Scandinavica; 71; 3-4; 5-2013; 416-423
dc.identifier.issn
0001-6357
dc.identifier.uri
http://hdl.handle.net/11336/23552
dc.description.abstract
OBJECTIVE: To evaluate the mechanisms of microbial interaction between the oral pathogens Candida albicans and Streptococcus mutans. MATERIALS AND METHODS: Growth kinetics for the two micro-organisms, cultured individually or together, were followed experimentally for 36 h. The different growth curves were analysed by means of mathematical modelling. RESULTS: Under the experimental conditions, S. mutans final concentration, when grown individually, was 5-times that of C. albicans. Contrarily, when both micro-organisms grew together, this ratio was inversed and C. albicans final concentration was even higher than that of S. mutans. When both micro-organisms share the niche, a model including linear competition among one another was best suited to reproduce the experimental observations. The results of this model show that the initial growth rates of both species are positively influenced by their mutual interaction. However, at longer incubation times, C. albicans prevents bacterial growth and achieves concentrations 4-times higher than when grown individually. CONCLUSIONS: The results suggest that C. albicans biofilm formation could be potentiated by the presence of S. mutans by two mechanisms: synergically at short times and by competition at longer periods.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Taylor & Francis
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Oral Microbiology
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Biofilms
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Streptococcus
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Candida
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Computational Models
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Ética Médica
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Ciencias de la Salud
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Mechanisms of interaction between Candida albicans and Streptococcus mutans: An experimental and mathematical modelling study
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-09-01T17:44:50Z
dc.journal.volume
71
dc.journal.number
3-4
dc.journal.pagination
416-423
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Brusca, María Isabel. Universidad Nacional de la Plata. Facultad de Odontologia; Argentina
dc.description.fil
Fil: Irastorza, Ramiro Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina
dc.description.fil
Fil: Cattoni, Diego Ignacio. Universite Montpellier II; Francia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Ozu, Marcelo. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Ciencias Fisiológicas. Laboratorio de Biomembranas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Chara, Osvaldo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina. Universität Dresden; Alemania
dc.journal.title
Acta Odontologica Scandinavica
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.3109/00016357.2012.690530
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3109/00016357.2012.690530
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