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dc.contributor.author
Bellino Ambort, Carolina Dianela  
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Herrera, Fernando Enrique  
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Rodrigues, Daniel Enrique  
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Garay, A. Sergio  
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Huck, Sofía Victoria  
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Reinheimer, Renata  
dc.date.available
2024-05-15T13:05:57Z  
dc.date.issued
2024-05  
dc.identifier.citation
Bellino Ambort, Carolina Dianela; Herrera, Fernando Enrique; Rodrigues, Daniel Enrique; Garay, A. Sergio; Huck, Sofía Victoria; et al.; Molecular Evolution of RAMOSA1 (RA1) in Land Plants; MDPI; Biomolecules; 14; 5; 5-2024; 1-21  
dc.identifier.issn
2218-273X  
dc.identifier.uri
http://hdl.handle.net/11336/235408  
dc.description.abstract
RAMOSA1 (RA1) is a Cys2-His2-type (C2H2) zinc finger transcription factor that controlsplant meristem fate and identity and has played an important role in maize domestication. Despiteits importance, the origin of RA1 is unknown, and the evolution in plants is only partially understood.In this paper, we present a well-resolved phylogeny based on 73 amino acid sequences from48 embryophyte species. The recovered tree topology indicates that, during grass evolution, RA1arose from two consecutive SUPERMAN duplications, resulting in three distinct grass sequencelineages: RA1-like A, RA1-like B, and RA1; however, most of these copies have unknown functions.Our findings indicate that RA1 and RA1-like play roles in the nucleus despite lacking a traditionalnuclear localization signal. Here, we report that copies diversified their coding region and, with it,their protein structure, suggesting different patterns of DNA binding and protein–protein interaction.In addition, each of the retained copies diversified regulatory elements along their promoter regions,indicating differences in their upstream regulation. Taken together, the evidence indicates that theRA1 and RA1-like gene families in grasses underwent subfunctionalization and neofunctionalizationenabled by gene duplication.  
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application/pdf  
dc.language.iso
eng  
dc.publisher
MDPI  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/  
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ZINC FINGER  
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EMBRYOPHYTE  
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PHYLOGENY  
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PARALOGS  
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COLLINEARITY  
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NUCLEAR LOCALIZATION  
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SECONDARY STRUCTURE  
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DIVERGENT MOTIFS  
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PROMOTER  
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Bioquímica y Biología Molecular  
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Ciencias Biológicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Molecular Evolution of RAMOSA1 (RA1) in Land Plants  
dc.type
info:eu-repo/semantics/article  
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info:ar-repo/semantics/artículo  
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info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-05-15T13:03:44Z  
dc.journal.volume
14  
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5  
dc.journal.pagination
1-21  
dc.journal.pais
Suiza  
dc.description.fil
Fil: Bellino Ambort, Carolina Dianela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina  
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Fil: Herrera, Fernando Enrique. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
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Fil: Rodrigues, Daniel Enrique. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
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Fil: Garay, A. Sergio. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina  
dc.description.fil
Fil: Huck, Sofía Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina  
dc.description.fil
Fil: Reinheimer, Renata. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Agrobiotecnología del Litoral. Universidad Nacional del Litoral. Instituto de Agrobiotecnología del Litoral; Argentina  
dc.journal.title
Biomolecules  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2218-273X/14/5/550  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/biom14050550