Artículo
Bioinorganic chemistry of trace elements: Possible role in the epigenetic modulation of homoeostatic processes in complex organisms
Ratti, Silvia Gabriela; Cioccale, Marcela Alejandra; Carignano, Claudio Alejandro
; Alvarez Toro, Edgardo Orozimbo
Fecha de publicación:
10/2013
Editorial:
American Scientific Publishers
Revista:
American Journal of Neuroprotection and Neuroregeneration
ISSN:
1947-2951
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Trace elements are well known in the geochemistry disciplines. However, its relationship to the biological and medical sciences is very recent. In spite that knowledge about the influence of environment in living processes is a traditional concept, until about the middle part of the 20 century, the possible influence on physiological functions of chemical elements present in waters and soil surrounding man habitat was not particularly investigated. Principal concern was concentrated to evaluate toxic actions of chemical elements on living systems. However, evidence showing that chemical elements are able to interact with enzymes, transcription factors and DNA in several living systems, put the inorganic elements into a new perspective. Higher concentrations of inorganic elements in the environment do not necessarily must be the only requirement for biological interactions in living systems. In the present paper historical aspects, some chemical properties of trace elements, an emphasized discussion about selenium and tellurium on functional processes in living systems are reviewed. In addition, hypothesis about the role of trace elements on epigenetic changes in the expression of gene action is also discussed.
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Colecciones
Articulos(CICTERRA)
Articulos de CENTRO DE INVEST.EN CS.DE LA TIERRA
Articulos de CENTRO DE INVEST.EN CS.DE LA TIERRA
Articulos(IMBECU)
Articulos de INST. DE MEDICINA Y BIO. EXP. DE CUYO
Articulos de INST. DE MEDICINA Y BIO. EXP. DE CUYO
Citación
Ratti, Silvia Gabriela; Cioccale, Marcela Alejandra; Carignano, Claudio Alejandro; Alvarez Toro, Edgardo Orozimbo; Bioinorganic chemistry of trace elements: Possible role in the epigenetic modulation of homoeostatic processes in complex organisms; American Scientific Publishers; American Journal of Neuroprotection and Neuroregeneration; 5; 1; 10-2013; 17-24
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