Mostrar el registro sencillo del ítem
dc.contributor.author
Cuesta Martínez, Sergio
dc.contributor.author
Ruiz Leyva, Leandro
dc.contributor.author
Jiménez García, Ana María
dc.contributor.author
Aparicio Mescua, Teresa
dc.contributor.author
López Guarnido, Olga
dc.contributor.author
Pautassi, Ricardo Marcos
dc.contributor.author
Moron, Ignacio
dc.contributor.author
Cendán, Cruz Miguel
dc.date.available
2024-03-22T14:57:19Z
dc.date.issued
2023-07
dc.identifier.citation
Cuesta Martínez, Sergio; Ruiz Leyva, Leandro; Jiménez García, Ana María; Aparicio Mescua, Teresa; López Guarnido, Olga; et al.; Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats; Bio-protocol LLC; Bio-protocol; 13; 15; 7-2023; 1-12
dc.identifier.issn
2331-8325
dc.identifier.uri
http://hdl.handle.net/11336/231333
dc.description.abstract
Developing valid animal models of excessive alcohol (ethanol) and/or highly palatable food self-administration is an essential task to elucidate the neurobiological mechanisms that underlie these behaviors. Previous work has highlighted that ethanol self-administration is modulated by both the induction of aversive states (i.e., stress or frustration) and by the concurrent availability of appetitive stimuli (e.g., food). In our protocol, rats are food deprived for three days until they reach 82%?85% of their ad libitum weight. After that, rats are exposed daily for 10 days to a brief binge or control eating experience with highly sugary and palatable food (i.e., the ingestion of 11.66 and 0.97 kcal/3 min, respectively), which is followed by a two-bottle-choice test (ethanol vs. water) in their home cages for 90 min. This model induces robust binge eating, which is followed by a selective increase in ethanol self-administration. Therefore, this protocol allows to study: a) behavioral and neurobiological factors related to binge eating, b) different stages of alcohol use, and c) interactions between the latter and other addictive-like behaviors, like binge eating.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Bio-protocol LLC
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Alcohol
dc.subject
Binge drinking
dc.subject
Binge eating
dc.subject
Addiction
dc.subject.classification
Drogadicción
dc.subject.classification
Ciencias de la Salud
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Binging from food to alcohol: A sequential interaction between binging behaviors in male wistar rats
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-03-08T14:30:59Z
dc.journal.volume
13
dc.journal.number
15
dc.journal.pagination
1-12
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Cuesta Martínez, Sergio. Universidad de Granada; España
dc.description.fil
Fil: Ruiz Leyva, Leandro. Universidad de Granada; España
dc.description.fil
Fil: Jiménez García, Ana María. Universidad de Granada; España
dc.description.fil
Fil: Aparicio Mescua, Teresa. Universidad de Granada; España
dc.description.fil
Fil: López Guarnido, Olga. Universidad de Granada; España
dc.description.fil
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba; Argentina
dc.description.fil
Fil: Moron, Ignacio. Universidad de Granada; España
dc.description.fil
Fil: Cendán, Cruz Miguel. Universidad de Granada; España
dc.journal.title
Bio-protocol
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://doi.org/10.21769/BioProtoc.4781
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://bio-protocol.org/en/bpdetail?id=4781&type=0
Archivos asociados