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dc.contributor.author
Ponsone, Maria Lorena
dc.contributor.author
Kuhn, Yamila Gisele
dc.contributor.author
Schmidt Heydt, M.
dc.contributor.author
Geisen, R.
dc.contributor.author
Chulze, Sofia Noemi
dc.date.available
2017-08-24T19:32:44Z
dc.date.issued
2013-06
dc.identifier.citation
Ponsone, Maria Lorena; Kuhn, Yamila Gisele; Schmidt Heydt, M.; Geisen, R.; Chulze, Sofia Noemi; Effect of Kluyveromyces thermotolerans on polyketide synthase gene expression and ochratoxin accumulation by Penicillium and Aspergillus; Wageningen Academic Publishers; World Mycotoxin Journal; 6; 3; 6-2013; 291-297
dc.identifier.issn
1875-0710
dc.identifier.uri
http://hdl.handle.net/11336/22949
dc.description.abstract
In a previous study, it was demonstrated that Kluyveromyces thermotolerans strains can reduce both growth and ochratoxin A (OTA) accumulation by Aspergillus section Nigri strains. There is no information about the mechanisms related to this reduction. A viable hypothesis can be that the presence of biocontrol agents can affect OTA biosynthesis by influencing the transcriptional activity of the polyketide synthase (pks) gene, one of the key enzymes in the OTA biosynthetic pathway. The aims of this work were to determine the effect of two selected strains of K. thermotolerans as potential biocontrol agents and to evaluate if their presence can affect the otapks gene expression of ochratoxigenic Aspergillus and Penicillium species. Growth, OTA and ochratoxin B (OTB) biosynthesis by the fungal strains at the phenotypic and molecular levels were monitored. The results obtained showed that both K. thermotolerans strains evaluated had a strong influence on growth, OTA and OTB biosynthesis, and expression of the mycotoxin biosynthesis genes. However, no direct correlation between the influence of the biocontrol yeasts on pks gene expression, OTA and OTB production could be found. These results could indicate an inhibitory mechanism by the yeasts, which apparently involve a post-transcriptional mechanism. The data obtained could imply that the production of mycotoxins can be regarded as a kind of adaptation mechanism to environmental stress conditions by these mycotoxigenic species.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wageningen Academic Publishers
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Biocontrol
dc.subject
Kuyveromyces Thermotolerans
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Ochratoxigenic Species
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Ochratoxins
dc.subject.classification
Bioquímica y Biología Molecular
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Ciencias Biológicas
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
dc.title
Effect of Kluyveromyces thermotolerans on polyketide synthase gene expression and ochratoxin accumulation by Penicillium and Aspergillus
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-08-24T18:02:18Z
dc.identifier.eissn
1875-0796
dc.journal.volume
6
dc.journal.number
3
dc.journal.pagination
291-297
dc.journal.pais
Países Bajos
dc.description.fil
Fil: Ponsone, Maria Lorena. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Kuhn, Yamila Gisele. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Schmidt Heydt, M.. Max Rubner Institut; Alemania
dc.description.fil
Fil: Geisen, R.. Max Rubner Institut; Alemania
dc.description.fil
Fil: Chulze, Sofia Noemi. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
World Mycotoxin Journal
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3920/WMJ2012.1532
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.wageningenacademic.com/doi/10.3920/WMJ2012.1532
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