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dc.contributor.author
Higa, Leticia Herminia
dc.contributor.author
Schilrreff, Priscila
dc.contributor.author
Perez, Ana Paula
dc.contributor.author
Morilla, María José
dc.contributor.author
Romero, Eder Lilia
dc.date.available
2017-08-24T19:28:19Z
dc.date.issued
2013-02
dc.identifier.citation
Higa, Leticia Herminia; Schilrreff, Priscila; Perez, Ana Paula; Morilla, María José; Romero, Eder Lilia; The intervention of Nanotechnology against epithelial fungal diseases; American Scientific Publishers; Journal of Biomaterials and Tissue Engineering; 3; 1; 2-2013; 70-88
dc.identifier.issn
2157-9083
dc.identifier.uri
http://hdl.handle.net/11336/22944
dc.description.abstract
Fungal infections can attack epithelial tissues and, according to the immunological state of the patient, some of them invade deeper organs, becoming seriously life compromising. Besides, bloodstream and local infections associated with intravascular devices constitute a significant problem associated with increased mortality. Topical therapy is desirable since, in addition to targeting the site of infection, it reduces the risk of systemic side effects and increases patient compliance. In this review we describe the pros and cons of using nano-objects that being toxic in nature could be used to cover surfaces of medical devices, or can act as carriers for targeted delivery of antifungals to skin. Non-toxic nano-objects were also included because they improve the ocular delivery of antifungals, classically suffering from ineffective topical administration, difficult access for systemic medication or local invasive administration. The new preclinical developments of nanoparticulate agents against cutaneous and ocular mycosis are grouped in three main sections: (1) In vitro antifungal activity of metallic nanoparticles, (2) In vitro and in vivo antifungal activity of non metallic nanoparticles (3) Ocular delivery of non metallic nanoparticles.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
American Scientific Publishers
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Nano-Objects
dc.subject
Metallic Nanoparticles
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Ephitelia
dc.subject
Fungi
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Nano-materiales
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Nanotecnología
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INGENIERÍAS Y TECNOLOGÍAS
dc.title
The intervention of Nanotechnology against epithelial fungal diseases
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-08-22T21:23:55Z
dc.identifier.eissn
2157-9091
dc.journal.volume
3
dc.journal.number
1
dc.journal.pagination
70-88
dc.journal.pais
Estados Unidos
dc.journal.ciudad
California
dc.description.fil
Fil: Higa, Leticia Herminia. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Schilrreff, Priscila. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Perez, Ana Paula. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Morilla, María José. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Romero, Eder Lilia. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.journal.title
Journal of Biomaterials and Tissue Engineering
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/contentone/asp/jbte/2013/00000003/00000001/art00006
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1166/jbt.2013.1065
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.aspbs.com/jbt/contents_jbt2013.htm#v3n1


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