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dc.contributor.author
Ciapponi, Agustín  
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Bardach, Ariel Esteban  
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Sandoval, María Macarena  
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Palermo, María Carolina  
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Navarro, Emiliano  
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Espinal, Carlos  
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Quirós, Rodolfo  
dc.date.available
2024-02-29T12:12:43Z  
dc.date.issued
2023-11  
dc.identifier.citation
Ciapponi, Agustín; Bardach, Ariel Esteban; Sandoval, María Macarena; Palermo, María Carolina; Navarro, Emiliano; et al.; Systematic Review and Meta-analysis of Deaths Attributable to Antimicrobial Resistance, Latin America; Centers Disease Control; Emerging Infectious Diseases; 29; 11; 11-2023; 2335-2344  
dc.identifier.issn
1080-6040  
dc.identifier.uri
http://hdl.handle.net/11336/228915  
dc.description.abstract
Antimicrobial resistance is a pressing global health concern, leading to 4.95 million deaths in 2019. We conducted a systematic review and meta-analysis to assess the lethality attributed to infections caused by multidrug-resistant organisms (MDROs) in Latin America and the Caribbean. A comprehensive search of major databases retrieved relevant studies from 2000–2022. We included 54 observational studies, primarily from Brazil, Argentina, and Colombia. The most commonly studied organism was methicillin-resistant Staphylococcus aureus. The overall unadjusted case fatality rate related to MDROs was 45.0%; higher adjusted lethality was observed in persons infected with MDROs than in those infected with other pathogens (adjusted odds ratio 1.93, 95% CI 1.58–2.37). A higher lethality rate was seen in patients who did not receive appropriate empirical treatment (odds ratio 2.27, 95% CI 1.44–3.56). These findings underscore the increased lethality associated with antimicrobial resistance in Latin America and the Caribbean.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Centers Disease Control  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Antimicrobial resistance  
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Latin America  
dc.subject.classification
Epidemiología  
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Ciencias de la Salud  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Systematic Review and Meta-analysis of Deaths Attributable to Antimicrobial Resistance, Latin America  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-02-28T09:53:40Z  
dc.journal.volume
29  
dc.journal.number
11  
dc.journal.pagination
2335-2344  
dc.journal.pais
Estados Unidos  
dc.journal.ciudad
Atlanta  
dc.description.fil
Fil: Ciapponi, Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina  
dc.description.fil
Fil: Bardach, Ariel Esteban. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina  
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Fil: Sandoval, María Macarena. Instituto de Efectividad Clínica y Sanitaria; Argentina  
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Fil: Palermo, María Carolina. Instituto de Efectividad Clínica y Sanitaria; Argentina  
dc.description.fil
Fil: Navarro, Emiliano. Instituto de Efectividad Clínica y Sanitaria; Argentina  
dc.description.fil
Fil: Espinal, Carlos. Florida International University; Estados Unidos  
dc.description.fil
Fil: Quirós, Rodolfo. Florida International University; Estados Unidos. Sanatorio Las Lomas; Argentina  
dc.journal.title
Emerging Infectious Diseases  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3201/eid2911.230753  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://wwwnc.cdc.gov/eid/article/29/11/23-0753_article