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dc.contributor.author
Córdova Isaza, Andrea
dc.contributor.author
Jiménez Mármol, Sofía
dc.contributor.author
Guerra, Yasel
dc.contributor.author
Salas Sarduy, Emir
dc.date.available
2024-02-28T11:56:03Z
dc.date.issued
2023-02
dc.identifier.citation
Córdova Isaza, Andrea; Jiménez Mármol, Sofía; Guerra, Yasel; Salas Sarduy, Emir; Enzyme Inhibitors from Gorgonians and Soft Corals; Molecular Diversity Preservation International; Marine Drugs; 21; 2; 2-2023; 1-32
dc.identifier.issn
1660-3397
dc.identifier.uri
http://hdl.handle.net/11336/228704
dc.description.abstract
For decades, gorgonians and soft corals have been considered promising sources of bioactive compounds, attracting the interest of scientists from different fields. As the most abundant bioactive compounds within these organisms, terpenoids, steroids, and alkaloids have received the highest coverage in the scientific literature. However, enzyme inhibitors, a functional class of bioactive compounds with high potential for industry and biomedicine, have received much less notoriety. Thus, we revised scientific literature (1974–2022) on the field of marine natural products searching for enzyme inhibitors isolated from these taxonomic groups. In this review, we present representative enzyme inhibitors from an enzymological perspective, highlighting, when available, data on specific targets, structures, potencies, mechanisms of inhibition, and physiological roles for these molecules. As most of the characterization studies for the new inhibitors remain incomplete, we also included a methodological section presenting a general strategy to face this goal by accomplishing STRENDA (Standards for Reporting Enzymology Data) project guidelines.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Molecular Diversity Preservation International
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
ENZYME INHIBITORS
dc.subject
ENZYME KINETICS
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GORGONIAN
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INHIBITOR CHARACTERIZATION
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NATURAL PRODUCTS
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SOFT CORAL
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STRENDA GUIDELINES
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Métodos de Investigación en Bioquímica
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
dc.title
Enzyme Inhibitors from Gorgonians and Soft Corals
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2024-02-28T10:33:06Z
dc.journal.volume
21
dc.journal.number
2
dc.journal.pagination
1-32
dc.journal.pais
Suiza
dc.journal.ciudad
Basel
dc.description.fil
Fil: Córdova Isaza, Andrea. Universidad de Las Américas.; Ecuador
dc.description.fil
Fil: Jiménez Mármol, Sofía. Universidad de Las Américas.; Ecuador
dc.description.fil
Fil: Guerra, Yasel. Universidad de Las Américas.; Ecuador
dc.description.fil
Fil: Salas Sarduy, Emir. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. - Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones Biotecnológicas; Argentina
dc.journal.title
Marine Drugs
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://doi.org/10.3390/md21020104
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/md21020104
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