Artículo
Alzheimer's disease risk after COVID-19: a view from the perspective of the infectious hypothesis of neurodegeneration
Olivera, Eugenia
; Sáez, Albany; Carniglia, Lila
; Caruso, Carla Mariana
; Lasaga, Mercedes Isabel
; Durand, Daniela Elizabeth
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Fecha de publicación:
07/2023
Editorial:
Shenyang Editorial Dept Neural Regeneration Res
Revista:
Neural Regeneration Research
ISSN:
1673-5374
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
In light of the rising evidence of the association between viral and bacterial infections and neurodegeneration, we aimed at revisiting the infectious hypothesis of Alzheimer's disease and analyzing the possible implications of COVID-19 neurological sequelae in long-term neurodegeneration. We wondered how SARS-CoV-2 could be related to the amyloid-β cascade and how it could lead to the pathological hallmarks of the disease. We also predict a paradigm change in clinical medicine, which now has a great opportunity to conduct prospective surveillance of cognitive sequelae and progression to dementia in people who suffered severe infections together with other risk factors for Alzheimer's disease.
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Articulos(INBIOMED)
Articulos de INSTITUTO DE INVESTIGACIONES BIOMEDICAS
Articulos de INSTITUTO DE INVESTIGACIONES BIOMEDICAS
Citación
Olivera, Eugenia; Sáez, Albany; Carniglia, Lila; Caruso, Carla Mariana; Lasaga, Mercedes Isabel; et al.; Alzheimer's disease risk after COVID-19: a view from the perspective of the infectious hypothesis of neurodegeneration; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 18; 7; 7-2023; 1404-1410
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