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dc.contributor.author
Nyarko, Kwame A.
dc.contributor.author
Lopez Camelo, Jorge Santiago
dc.contributor.author
Castilla, Eduardo Enrique
dc.contributor.author
Wehby, George
dc.date.available
2017-08-16T23:42:25Z
dc.date.issued
2013-01
dc.identifier.citation
Nyarko, Kwame A.; Lopez Camelo, Jorge Santiago; Castilla, Eduardo Enrique; Wehby, George; Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples; Elsevier; Journal of Pediatrics; 162; 1; 1-2013; 42-49
dc.identifier.issn
0022-3476
dc.identifier.uri
http://hdl.handle.net/11336/22552
dc.description.abstract
OBJECTIVE: To evaluate if the association between prenatal care use and birth weight (BW) varies for infants with cleft lip and/or cleft palate (CL/P), classified into isolated and non-isolated forms, compared with unaffected infants. STUDY DESIGN: The study employed 2 datasets. The first included a multi-country sample of 2405 infants with CL/P and 24046 infants without CL/P born in 1996-2007 in South America. The second was a sample of 2122 infants with CL/P and 297415 without CL/P from the United States 2004 natality dataset. Separate analyses were performed for the South American and United States samples. The association between prenatal care and BW was evaluated separately for isolated CL/P, non-isolated CL/P, and unaffected infants using regression models adjusting for several background characteristics. RESULTS: Prenatal care was associated with improved BW for all infant groups, with greater BW increases for infants with CL/P particularly non-isolated forms. In the South American sample, BW increased by 108, 69, and 40 g on average per prenatal visit for infants with non-isolated CL/P, infants with isolated CL/P, and unaffected infants, respectively. In the United States sample, BW increased by 51, 21, and 16 g on average per prenatal visit for these infant groups, respectively. CONCLUSIONS: Prenatal care was associated with larger BW increases for pregnancies complicated with CL/P, particularly non-isolated forms, compared with unaffected pregnancies. Given that reduced BW is a well-recognized comorbidity of CL/P, the findings highlight the importance of prenatal care for at-risk pregnancies as a tertiary-prevention intervention to reduce the health burden of CL/P.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.subject
Birth Weight
dc.subject
Cleft Lip And/Or Cleft Palate
dc.subject
Latin American Collaborative Study of Congenital Malformations
dc.subject.classification
Ética Médica
dc.subject.classification
Ciencias de la Salud
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Does the Relationship between Prenatal Care and Birth Weight Vary by Oral Clefts? Evidence Using South American and United States Samples
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-08-07T16:22:23Z
dc.journal.volume
162
dc.journal.number
1
dc.journal.pagination
42-49
dc.journal.pais
Estados Unidos
dc.journal.ciudad
Nueva York
dc.description.fil
Fil: Nyarko, Kwame A.. University of Iowa; Estados Unidos
dc.description.fil
Fil: Lopez Camelo, Jorge Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; Brasil
dc.description.fil
Fil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínica "Norberto Quirno". CEMIC-CONICET.; Argentina. Instituto Oswaldo Cruz; Brasil
dc.description.fil
Fil: Wehby, George. University of Iowa; Estados Unidos
dc.journal.title
Journal of Pediatrics
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0022347612007287
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.jpeds.2012.06.040
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485451/
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