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dc.contributor.author
Rodriguez, Piuque Miguel  
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Ondarza, Paola Mariana  
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Miglioranza, Karina Silvia Beatriz  
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Ramirez, Cristina Lujan  
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Vera, Berta Emma  
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Muntaner, Celeste  
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Guiñazú, Natalia L.  
dc.date.available
2024-01-05T15:47:48Z  
dc.date.issued
2023-08  
dc.identifier.citation
Rodriguez, Piuque Miguel; Ondarza, Paola Mariana; Miglioranza, Karina Silvia Beatriz; Ramirez, Cristina Lujan; Vera, Berta Emma; et al.; Pesticides exposure in pregnant Argentinian women: Potential relations with the residence areas and the anthropometric neonate parameters; Pergamon-Elsevier Science Ltd; Chemosphere; 332; 8-2023; 1-9  
dc.identifier.issn
0045-6535  
dc.identifier.uri
http://hdl.handle.net/11336/222642  
dc.description.abstract
Intrauterine environment is the first chemical exposure scenario in life, through transplacental transfer. In this study, the aim was to determine concentrations of organochlorine pesticides (OCPs) and selected current use pesticides in the placentas of pregnant women from Argentina. Socio-demographic information, the mother's lifestyle and neonatal characteristics were also analysed and related to pesticides residue concentrations. Thus, 85 placentas were collected at birth, from an area of intensive fruit production for the international market, in Patagonia Argentina. Concentrations of 23 pesticides including, trifluralin (herbicide), the fungicides chlorothalonil and HCB, and the insecticides chlorpyrifos, HCHs, endosulfans, DDTs, chlordanes, heptachlors, drins and metoxichlor, were determined by GC-ECD and GC-MS. Results were first analysed all together and then grouped by their residential settings, in urban and rural groups. Total mean pesticide concentration was 582.6 ± 1034.4 ng/g lw, where DDTs (325.9 ± 950.3 ng/g lw) and chlorpyrifos (188.4 ± 365.4 ng/g lw) showed a high contribution. Pesticide levels found exceeded those reported in low, middle and high income countries from Europe, Asia and Africa. In general, pesticides concentrations were not associated with neonatal anthropometric parameters. When the results were analysed by residence place, significantly higher concentrations of total pesticides and chlorpyrifos (Mann Whitney test p = 0.0003 and p = 0.032, respectively) were observed in placentas collected from mothers living in rural settings compared to urban areas. Rural pregnant women presented the highest pesticide burden (5.9 μg), where DDTs and chlorpyrifos were the major constituents. These results suggested that all pregnant women are highly exposed to complex pesticide mixtures, including banned OCPs and the widely used chlorpyrifos. Based on the pesticide concentrations found, our results warn of possible health impacts from prenatal exposure through transplacental transfer. This is one of the first reports of both chlorpyrifos and chlorothalonil concentrations in placental tissue, and contributes to the knowledge of current pesticide exposure in Argentina.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Pergamon-Elsevier Science Ltd  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
CHLORPYRIFOS  
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ENVIRONMENTAL EXPOSURE  
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ORGANOCHLORINE PESTICIDES  
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ORGANOPHOSPHATE PESTICIDES  
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PLACENTA  
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PLACENTAL TRANSFER  
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Otras Ciencias de la Tierra y relacionadas con el Medio Ambiente  
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Ciencias de la Tierra y relacionadas con el Medio Ambiente  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Pesticides exposure in pregnant Argentinian women: Potential relations with the residence areas and the anthropometric neonate parameters  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-01-04T14:59:28Z  
dc.journal.volume
332  
dc.journal.pagination
1-9  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Rodriguez, Piuque Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue. Universidad Nacional del Comahue. Facultad de Ciencias Agrarias. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue; Argentina  
dc.description.fil
Fil: Ondarza, Paola Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Marinas y Costeras; Argentina  
dc.description.fil
Fil: Miglioranza, Karina Silvia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones Marinas y Costeras. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Instituto de Investigaciones Marinas y Costeras; Argentina  
dc.description.fil
Fil: Ramirez, Cristina Lujan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Química; Argentina  
dc.description.fil
Fil: Vera, Berta Emma. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue. Universidad Nacional del Comahue. Facultad de Ciencias Agrarias. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue; Argentina. Universidad Nacional del Comahue. Facultad de Medicina; Argentina  
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Fil: Muntaner, Celeste. Universidad Nacional del Comahue. Facultad de Medicina; Argentina  
dc.description.fil
Fil: Guiñazú, Natalia L.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue. Universidad Nacional del Comahue. Facultad de Ciencias Agrarias. Centro de Investigaciones en Toxicología Ambiental y Agrobiotecnología del Comahue; Argentina. Universidad Nacional del Comahue. Facultad de Ciencias del Ambiente y la Salud; Argentina  
dc.journal.title
Chemosphere  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0045653523010573  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.chemosphere.2023.138790