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dc.contributor.author
Margarit, David Hipólito  
dc.contributor.author
Reale, Marcela Verónica  
dc.contributor.author
Scagliotti, Ariel Fabricio  
dc.contributor.author
Romanelli, Lilia Mabel  
dc.date.available
2024-01-04T19:26:51Z  
dc.date.issued
2023-04  
dc.identifier.citation
Margarit, David Hipólito; Reale, Marcela Verónica; Scagliotti, Ariel Fabricio; Romanelli, Lilia Mabel; The role of Absorbing Markov Chains in childhood cancer; Cold Spring Harbor Laboratory Press; Biorxiv; 4-2023; 1-15  
dc.identifier.issn
2641-9165  
dc.identifier.uri
http://hdl.handle.net/11336/222474  
dc.description.abstract
Absorbing Markov Chains are an important mathematical tool used for different applications in science. On the other hand, cancer and its metastases in children have a significant impact on health due to their degree of lethality. Therefore, the aim of this work is to model the metastatic pathways of the main childhood cancers worldwide. The probabilities of generating metastases, from a primary site to secondary and tertiary sites, were characterized by constructing a directed graph and the associated transition matrix. In addition, the time of absorption and the probabilities of absorption by each absorbing state were calculated.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Cold Spring Harbor Laboratory Press  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ABSORBING MARKOV CHAINS  
dc.subject
METASTASIS  
dc.subject
MATHEMATICAL BIOLOGY  
dc.subject.classification
Otras Ciencias Físicas  
dc.subject.classification
Ciencias Físicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
The role of Absorbing Markov Chains in childhood cancer  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2024-01-03T12:40:21Z  
dc.journal.pagination
1-15  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Margarit, David Hipólito. Universidad Nacional de General Sarmiento; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Reale, Marcela Verónica. Universidad Nacional de General Sarmiento; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Matanza; Argentina  
dc.description.fil
Fil: Scagliotti, Ariel Fabricio. Universidad Tecnológica Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Romanelli, Lilia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de General Sarmiento; Argentina  
dc.journal.title
Biorxiv  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1101/2022.12.12.520113  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.biorxiv.org/content/10.1101/2022.12.12.520113v1  

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