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dc.contributor.author
Fuller, Barry J.  
dc.contributor.author
Petrenko, Alexander Y.  
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Rodriguez, Joaquin Valentin  
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Somov, Alexander Y.  
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Balaban, Cecilia Lucía  
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Guibert, Edgardo Elvio  
dc.date.available
2017-08-10T22:44:52Z  
dc.date.issued
2016-07  
dc.identifier.citation
Fuller, Barry J.; Petrenko, Alexander Y.; Rodriguez, Joaquin Valentin; Somov, Alexander Y.; Balaban, Cecilia Lucía; et al.; Biopreservation of Hepatocytes: Current Concepts on Hypothermic Preservation, Cryopreservation, And Vitrification; Cryo Letters; Cryo-letters; 37; 4; 7-2016; 432-452  
dc.identifier.issn
0143-2044  
dc.identifier.uri
http://hdl.handle.net/11336/22155  
dc.description.abstract
Isolated liver cells (primarily isolated hepatocytes) have found important applications in science and medicine over the past 40 years in a wide range of areas, including physiological studies, investigations on liver metabolism, organ preservation and drug de-toxification, experimental and clinical transplantation. An integral component of many of these works is the need to store the isolated cells, either for short or long-term periods. This review covers the biopreservation of liver cells, with a focus on the history of liver cell biopreservation, the application of hypothermia for short-term storage, standard cryopreservation methods for isolated hepatocytes, the biopreservation of other types of liver cells, and recent developments such as vitrification of hepatocytes. By understanding the basis for the different approaches, it will be possible to select the best options for liver cell biopreservation in different applications, and identify ways to improve preservation protocols for the future.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Cryo Letters  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Hepatocyte  
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Drying  
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Hipothermic Preservation  
dc.subject.classification
Ética Médica  
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Ciencias de la Salud  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Biopreservation of Hepatocytes: Current Concepts on Hypothermic Preservation, Cryopreservation, And Vitrification  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2017-08-04T13:53:29Z  
dc.journal.volume
37  
dc.journal.number
4  
dc.journal.pagination
432-452  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Fuller, Barry J.. University College London; Estados Unidos  
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Fil: Petrenko, Alexander Y.. Ukraine Academy of Sciences; Ucrania  
dc.description.fil
Fil: Rodriguez, Joaquin Valentin. Universidad Nacional de Rosario. Secretaria de Ciencia y Tecnica. Centro Binacional de Investigación en Criobiologia Clinica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Somov, Alexander Y.. Ukraine Academy of Sciences; Ucrania  
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Fil: Balaban, Cecilia Lucía. Universidad Nacional de Rosario. Secretaria de Ciencia y Tecnica. Centro Binacional de Investigación en Criobiologia Clinica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: Guibert, Edgardo Elvio. Universidad Nacional de Rosario. Secretaria de Ciencia y Tecnica. Centro Binacional de Investigación en Criobiologia Clinica y Aplicada; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.journal.title
Cryo-letters  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.ingentaconnect.com/contentone/cryo/cryo/2016/00000037/00000004/art00013