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dc.contributor.author
Santamaria Garcia, Hernando
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dc.contributor.author
Moguilner, Sebastian Gabriel
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Rodriguez Villagra, Odir Antonio
dc.contributor.author
Botero Rodriguez, Felipe
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Pina Escudero, Stefanie Danielle
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O’Donovan, Gary
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Albala, Cecilia
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Matallana, Diana
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Schulte, Michael
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Slachevsky, Andrea
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Yokoyama, Jennifer S.
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Possin, Katherine
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Ndhlovu, Lishomwa C.
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Al-Rousan, Tala
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Corley, Michael J.
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Kosik, Kenneth
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Muniz Terrera, Graciela
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Miranda, J. Jaime
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Ibañez, Agustin Mariano
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dc.date.available
2023-12-19T15:26:16Z
dc.date.issued
2023-02
dc.identifier.citation
Santamaria Garcia, Hernando; Moguilner, Sebastian Gabriel; Rodriguez Villagra, Odir Antonio; Botero Rodriguez, Felipe; Pina Escudero, Stefanie Danielle; et al.; The impacts of social determinants of health and cardiometabolic factors on cognitive and functional aging in Colombian underserved populations; Springer Science and Business Media Deutschland GmbH; GeroScience; 45; 4; 2-2023; 2405-2423
dc.identifier.issn
2509-2715
dc.identifier.uri
http://hdl.handle.net/11336/220822
dc.description.abstract
Global initiatives call for further understanding of the impact of inequity on aging across underserved populations. Previous research in low- and middle-income countries (LMICs) presents limitations in assessing combined sources of inequity and outcomes (i.e., cognition and functionality). In this study, we assessed how social determinants of health (SDH), cardiometabolic factors (CMFs), and other medical/social factors predict cognition and functionality in an aging Colombian population. We ran a cross-sectional study that combined theory- (structural equation models) and data-driven (machine learning) approaches in a population-based study (N = 23,694; M = 69.8 years) to assess the best predictors of cognition and functionality. We found that a combination of SDH and CMF accurately predicted cognition and functionality, although SDH was the stronger predictor. Cognition was predicted with the highest accuracy by SDH, followed by demographics, CMF, and other factors. A combination of SDH, age, CMF, and additional physical/psychological factors were the best predictors of functional status. Results highlight the role of inequity in predicting brain health and advancing solutions to reduce the cognitive and functional decline in LMICs.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Springer Science and Business Media Deutschland GmbH
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CARDIOMETABOLIC FACTORS
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COGNITION
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FUNCTIONALITY
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NATIONAL AGING POPULATION SURVEY
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SOCIAL DETERMINANTS OF HEALTH
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Neurociencias
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
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dc.title
The impacts of social determinants of health and cardiometabolic factors on cognitive and functional aging in Colombian underserved populations
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-12-07T15:35:11Z
dc.identifier.eissn
2509-2723
dc.journal.volume
45
dc.journal.number
4
dc.journal.pagination
2405-2423
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Santamaria Garcia, Hernando. Pontificia Universidad Javeriana; Colombia. Hospital Universitario San Ignacio; Colombia. University of California; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
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Fil: Moguilner, Sebastian Gabriel. Universidad de San Andrés; Argentina. Massachusetts General Hospital; Estados Unidos. Universidad Adolfo Ibañez; Chile
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Fil: Rodriguez Villagra, Odir Antonio. Universidad de Costa Rica; Costa Rica
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Fil: Botero Rodriguez, Felipe. Pontificia Universidad Javeriana; Colombia
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Fil: Pina Escudero, Stefanie Danielle. University of California; Estados Unidos
dc.description.fil
Fil: O’Donovan, Gary. Universidad Adolfo Ibañez; Chile. Universidad de los Andes; Colombia
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Fil: Albala, Cecilia. Universidad de Chile; Chile
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Fil: Matallana, Diana. Fundacion Santa Fe de Bogota; Colombia. Hospital Universitario San Ignacio; Colombia. Pontificia Universidad Javeriana; Colombia
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Fil: Schulte, Michael. Universidad Adolfo Ibañez; Chile
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Fil: Slachevsky, Andrea. Universidad del Desarrollo; Chile. Universidad de Chile; Chile
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Fil: Yokoyama, Jennifer S.. University of California; Estados Unidos
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Fil: Possin, Katherine. University of California; Estados Unidos
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Fil: Ndhlovu, Lishomwa C.. Weill Cornell Medicine; Estados Unidos
dc.description.fil
Fil: Al-Rousan, Tala. University of California at San Diego; Estados Unidos
dc.description.fil
Fil: Corley, Michael J.. Weill Cornell Medicine; Estados Unidos
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Fil: Kosik, Kenneth. University of California; Estados Unidos
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Fil: Muniz Terrera, Graciela. University of Edinburgh; Reino Unido. Ohio University; Estados Unidos
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Fil: Miranda, J. Jaime. George Institute For Global Health; Australia. Cronicas Centro de Excelencia En Enfermedades Crónicas; Perú. Universidad Peruana Cayetano Heredia; Perú
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Fil: Ibañez, Agustin Mariano. Universidad de San Andrés; Argentina. Trinity College Dublin; Irlanda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of California; Estados Unidos. Universidad Adolfo Ibañez; Chile
dc.journal.title
GeroScience
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/s11357-023-00755-z
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007/s11357-023-00755-z
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