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dc.contributor.author
Roca, María
dc.contributor.author
Manes, Facundo Francisco
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Gleichgerrcht, Ezequiel
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Watson, Peter
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Ibañez, Agustin Mariano
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Thompson, Russell
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Torralva, Teresa
dc.contributor.author
Duncan, John
dc.date.available
2017-08-08T20:19:11Z
dc.date.issued
2013-03
dc.identifier.citation
Roca, María; Manes, Facundo Francisco; Gleichgerrcht, Ezequiel; Watson, Peter; Ibañez, Agustin Mariano; et al.; Intelligence and executive functions in frontotemporal dementia; Elsevier; Neuropsychologia; 51; 4; 3-2013; 725-730
dc.identifier.issn
0028-3932
dc.identifier.uri
http://hdl.handle.net/11336/22063
dc.description.abstract
Recently (Roca et al. (2010), we used the relationship with general intelligence (Spearman’s g) to define two sets of frontal lobe or “executive” tests. For one group, including Wisconsin card sorting and verbal fluency, reduction in g entirely explained the deficits found in frontal patients. For another group, including tests of social cognition and multitasking, frontal deficits remained even after correction for g. Preliminary evidence suggested a link of the latter tasks to more anterior frontal regions. Here we develop this distinction in the context of behavioural-variant frontotemporal dementia (bvFTD), a disorder which progressively affects frontal lobe cortices. In bvFTD, some executive tests, including tests of social cognition and multitasking, decline from the early stage of the disease, while others, including classical executive tests such as Wisconsin card sorting, verbal fluency or Trail Making Test part B, show deficits only later on. Here we show that, while deficits in the classical executive tests are entirely explained by g, deficits in the social cognition and multitasking tests are not. The results suggest a relatively selective cognitive deficit at mild stages of the disease, followed by more widespread cognitive decline well predicted by g.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
Frontotemporal Dementia
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Fluid Intelligence
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Executive Functions
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Theory Ofmind
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Multitasking
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Ética Médica
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Intelligence and executive functions in frontotemporal dementia
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-08-07T16:22:19Z
dc.journal.volume
51
dc.journal.number
4
dc.journal.pagination
725-730
dc.journal.pais
Países Bajos
dc.journal.ciudad
Ámsterdam
dc.description.fil
Fil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Manes, Facundo Francisco. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Neurología Cognitiva; Argentina
dc.description.fil
Fil: Gleichgerrcht, Ezequiel. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina
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Fil: Watson, Peter. Medical Research Council. Cognition and Brain Sciences Unit; Reino Unido
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Fil: Ibañez, Agustin Mariano. Instituto de Neurología Cognitiva; Argentina. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
dc.description.fil
Fil: Thompson, Russell. Medical Research Council. Cognition and Brain Sciences Unit; Reino Unido
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Fil: Torralva, Teresa. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina
dc.description.fil
Fil: Duncan, John. Medical Research Council. Cognition and Brain Sciences Unit; Reino Unido
dc.journal.title
Neuropsychologia
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0028393213000146
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.neuropsychologia.2013.01.008
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