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dc.contributor.author
Jiménez, José María
dc.contributor.author
Morales, Rosa María
dc.contributor.author
Menéndez Buxadera, Alberto
dc.contributor.author
Demyda-peyrás, Sebastian
dc.contributor.author
Laseca, Nora
dc.contributor.author
Molina, Antonio
dc.date.available
2023-12-04T15:04:49Z
dc.date.issued
2023-01
dc.identifier.citation
Jiménez, José María; Morales, Rosa María; Menéndez Buxadera, Alberto; Demyda-peyrás, Sebastian; Laseca, Nora; et al.; Estimation of the Genetic Components of (Co)variance and Preliminary Genome-Wide Association Study for Reproductive Efficiency in Retinta Beef Cattle; Multidisciplinary Digital Publishing Institute; Animals; 13; 3; 1-2023; 1-19
dc.identifier.issn
2076-2615
dc.identifier.uri
http://hdl.handle.net/11336/219203
dc.description.abstract
In this study, we analyzed the variation of reproductive efficiency, estimated as the deviation between the optimal and real parity number of females at each stage of the cow’s life, in 12,554 cows belonging to the Retinta Spanish cattle breed, using classical repeatability and random regression models. The results of the analyses using repeatability model and the random regression model suggest that reproductive efficiency is not homogeneous throughout the cow’s life. The h2 estimate for this model was 0.30, while for the random regression model it increased across the parities, from 0.24 at the first calving to 0.51 at calving number 9. Additionally, we performed a preliminary genome-wide association study for this trait in a population of 252 Retinta cows genotyped using the Axiom Bovine Genotyping v3 Array. The results showed 5 SNPs significantly associated with reproductive efficiency, located in two genomic regions (BTA4 and BTA28). The functional analysis revealed the presence of 5 candidate genes located within these regions, which were previously involved in different aspects related to fertility in cattle and mice models. This new information could give us a better understanding of the genetic architecture of reproductive traits in this species, as well as allow us to accurately select more fertile cows.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Multidisciplinary Digital Publishing Institute
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
AGE AT FIRST CALVING
dc.subject
CALVING INTERVAL
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GWAS
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RANDOM REGRESSION MODEL
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REPRODUCTIVE EFFICIENCY
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RETINTA BEEF CATTLE
dc.subject.classification
Tecnología GM, clonación de ganado, selección asistida, diagnósticos, tecnología de producción de biomasa, etc.
dc.subject.classification
Biotecnología Agropecuaria
dc.subject.classification
CIENCIAS AGRÍCOLAS
dc.title
Estimation of the Genetic Components of (Co)variance and Preliminary Genome-Wide Association Study for Reproductive Efficiency in Retinta Beef Cattle
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-12-04T11:50:35Z
dc.journal.volume
13
dc.journal.number
3
dc.journal.pagination
1-19
dc.journal.pais
Suiza
dc.description.fil
Fil: Jiménez, José María. No especifíca;
dc.description.fil
Fil: Morales, Rosa María. Universidad de Córdoba; España
dc.description.fil
Fil: Menéndez Buxadera, Alberto. Universidad de Córdoba; España
dc.description.fil
Fil: Demyda-peyrás, Sebastian. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; Argentina
dc.description.fil
Fil: Laseca, Nora. Universidad de Córdoba; España
dc.description.fil
Fil: Molina, Antonio. Universidad de Córdoba; España
dc.journal.title
Animals
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2076-2615/13/3/501
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3390/ani13030501
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