Artículo
Recategorisation of body mass index to achieve andrological predictive power: A study in more than 20000 patients
Ramirez, Nicolas
; Molina, Rosa Inés; Tissera, Andrea Daniela; Luque, Eugenia Mercedes
; Torres, Pedro Javier
; Bianconi, Santiago
; Beltramone, Fernando; Sad Larcher, José; Estofán, Gustavo; Mangeaud, Arnaldo Pedro; Martini, Ana Carolina
Fecha de publicación:
03/2020
Editorial:
Csiro Publishing
Revista:
Reproduction Fertility and Development
ISSN:
1031-3613
e-ISSN:
1448-5990
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The aim of this study was to recategorise body mass index (BMI) in order to classify patients according to their risk of semen abnormalities. Patients (n = 20 563) presenting at an andrology laboratory were classified into five groups according to BMI: underweight (BMI <20 kg m-2), normal weight (BMI 20-24.9 kg m-2), overweight (BMI 25-29.9 kg m-2), obese (BMI 30-39.9 kg m-2) and morbidly obese (BMI >40 kg m-2). Semen quality was evaluated to determine: (1) differences between groups using analysis of variance (ANOVA); (2) the chances of semen abnormalities (using generalised linear models, Chi-squared tests and odds ratios); (3) reference BMI values with andrological predictive power (multivariate conglomerate analyses and multivariate analysis of variance (MANOVA)); and (4) expected values of abnormalities for each new group resulting from BMI recategorisation. Morbidly obese and underweight patients exhibited the highest decrease in semen quality and had higher chances of semen abnormalities. The smallest number of sperm abnormalities was found at a BMI of 27 kg m-2. Four reference values were identified, recategorising BMI into four groups according to their risk of semen abnormalities (from lowest to highest risk): Group1,BMI between 20 and 32 kg m-2; Group2, BMI <20 and BMI >32-37 kg m-2; Group3, BMI >37-42 kg m-2; and Group4, BMI >42 kg m-2. A BMI <20 or >32 kg m-2 is negatively associated with semen quality; these negative associations on semen quality increase from a BMI >37 kg m-2 and increase even further for BMI >42 kg m-2. The BMI recategorisation in this study has andrological predictive power.
Palabras clave:
MORBID OBESITY
,
OBESITY
,
SEMEN
,
SPERM QUALITY
,
UNDERWEIGHT
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Identificadores
Colecciones
Articulos(INICSA)
Articulos de INSTITUTO DE INVESTIGACIONES EN CIENCIAS DE LA SALUD
Articulos de INSTITUTO DE INVESTIGACIONES EN CIENCIAS DE LA SALUD
Citación
Ramirez, Nicolas; Molina, Rosa Inés; Tissera, Andrea Daniela; Luque, Eugenia Mercedes; Torres, Pedro Javier; et al.; Recategorisation of body mass index to achieve andrological predictive power: A study in more than 20000 patients; Csiro Publishing; Reproduction Fertility and Development; 32; 7; 3-2020; 648-656
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