Artículo
Beta-lactam antibiotics and viridans group streptococci
Título:
Antibióticos beta-lactámicos y estreptococos grupo viridans
Lopardo, Horacio Angel; Vigliarolo, Laura; Bonofiglio, Laura
; Gagetti, Paula Silvana; García Gabarrot, Gabriela; Kaufman, Sara; Mollerach, Marta Eugenia
; Toresani, Inés; Von Specht, Martha Helena
Fecha de publicación:
10/2022
Editorial:
Asociación Argentina de Microbiología
Revista:
Revista Argentina de Microbiología
ISSN:
0325-7541
e-ISSN:
1851-7617
Idioma:
Español
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The aim of this review is to present an update on the susceptibility of viridans group streptococci (VGS) to β-lactam antimicrobials, with emphasis on the Argentinean scenario. VGS are a heterogeneous group including five groups of species, each one exhibiting peculiar susceptibility patterns to penicillin (PEN). Species of the Streptococcus mitis group are frequently nonsusceptible to PEN. PEN resistance is associated with changes in PEN-binding proteins. In Argentina, one to two thirds of VGS are nonsusceptible to PEN. Third generation cephalosporins and carbapenems are currently more effective in vitro than PEN against VGS. Mortality was associated to nonsusceptibility to PEN in at least two studies involving patients with bacteremia caused by VGS. Treatment of endocarditis due to VGS should be adjusted/to the PEN susceptibility of the isolates. Vancomycin may be an alternative choice for treating endocarditis caused by PEN-resistant isolates (MIC ≥ 4 μg/ml).
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Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Lopardo, Horacio Angel; Vigliarolo, Laura; Bonofiglio, Laura; Gagetti, Paula Silvana; García Gabarrot, Gabriela; et al.; Beta-lactam antibiotics and viridans group streptococci ; Asociación Argentina de Microbiología; Revista Argentina de Microbiología; 54; 4; 10-2022; 335-343
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