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dc.contributor.author
Vinderola, Celso Gabriel
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dc.contributor.author
Sanders, Mary Ellen
dc.contributor.author
Salminen, Seppo
dc.contributor.author
Szajewska, Hania
dc.date.available
2023-11-10T12:40:52Z
dc.date.issued
2022-12
dc.identifier.citation
Vinderola, Celso Gabriel; Sanders, Mary Ellen; Salminen, Seppo; Szajewska, Hania; Postbiotics: The concept and their use in healthy populations; Frontiers Media; Frontiers in Nutrition; 9; 12-2022; 1-7
dc.identifier.issn
2296-861X
dc.identifier.uri
http://hdl.handle.net/11336/217712
dc.description.abstract
The term postbiotic was recently defined by an panel of scientists convened by the International Scientific Association of Probiotics and Prebiotics as “a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” This definition focused on the progenitor microbial cell or cell fragments, not just metabolites, proteins or carbohydrates they might produce. Although such microbe-produced constituents may be functional ingredients of the preparation, they are not required to be present in a postbiotic according to this definition. In this context, terms previously used such as paraprobiotics, ghostbiotics, heat-inactivated probiotics, non-viable probiotics, cell fragments or cell lysates, among others, align with the term postbiotics as conceived by this definition. The applications of postbiotics to infant nutrition and pediatric and adult gastroenterology, mainly, are under development. Some applications for skin health are also underway. As postbiotics are composed of inanimate microorganisms, they cannot colonize the host. However, they can in theory modify the composition or functions of the host microbiota, although evidence for this is scarce. Clinical results are promising, but, overall, there is limited evidence for postbiotics in healthy populations. For example, postbiotics have been studied in fermented infant formulas. The regulation of the term postbiotic is still in its infancy, as no government or international agency around the world has yet incorporated this term in their regulation.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Frontiers Media
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
CLINICAL STUDIES
dc.subject
DEFINITIONS
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HEALTHY POPULATION
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MICROBIOME
dc.subject
POSTBIOTICS
dc.subject.classification
Otras Ingenierías y Tecnologías
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dc.subject.classification
Otras Ingenierías y Tecnologías
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dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
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dc.title
Postbiotics: The concept and their use in healthy populations
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-11-09T13:47:10Z
dc.journal.volume
9
dc.journal.pagination
1-7
dc.journal.pais
Estados Unidos
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dc.description.fil
Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
dc.description.fil
Fil: Sanders, Mary Ellen. International Scientific Association For Probiotics And Prebiotics; Estados Unidos
dc.description.fil
Fil: Salminen, Seppo. University of Turku; Finlandia
dc.description.fil
Fil: Szajewska, Hania. Medical University Of Warsaw; Polonia
dc.journal.title
Frontiers in Nutrition
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fnut.2022.1002213
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