Artículo
Differences in learning and memory between middle-aged female and male rats
Colettis, Natalia Claudia
; Habif, Martin
; Oberholzer, María Victoria
; Filippin, Federico; Jerusalinsky, Diana Alicia
Fecha de publicación:
03/2022
Editorial:
Cold Spring Harbor Laboratory Press
Revista:
Learning & Memory (Cold Spring Harbor, N.Y.)
ISSN:
1072-0502
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
We observed differences in cognitive functions between middle-aged female and male Wistar rats. Both (like youngsters) discriminated new versus familiar objects, showing similar short- and long-term memory (STM and LTM, respectively). Only females show robust LTM for new location of an object. Both successfully form LTM of inhibitory avoidance, though males appeared to be amnesic for memory persistence. Habituation, locomotion, horizontal exploration, "stereotypies,"fear, and anxiety-like behavior were similar for both, while vertical exploration was significantly higher in middleaged and younger females. Therefore, sex-dependent differences in some cognitive functions and behaviors must be considered when designing and interpreting learning and memory studies.
Palabras clave:
Sexual dimorphism
,
Memory
,
Middle-aged rats
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(IQUIFIB)
Articulos de INST.DE QUIMICA Y FISICO-QUIMICA BIOLOGICAS "PROF. ALEJANDRO C. PALADINI"
Articulos de INST.DE QUIMICA Y FISICO-QUIMICA BIOLOGICAS "PROF. ALEJANDRO C. PALADINI"
Citación
Colettis, Natalia Claudia; Habif, Martin; Oberholzer, María Victoria; Filippin, Federico; Jerusalinsky, Diana Alicia; Differences in learning and memory between middle-aged female and male rats; Cold Spring Harbor Laboratory Press; Learning & Memory (Cold Spring Harbor, N.Y.); 29; 5; 3-2022; 120-125
Compartir
Altmétricas