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dc.contributor.author
Mayorga, Luis Segundo  
dc.contributor.author
López, María José  
dc.contributor.author
Becker, Wayne M.  
dc.date.available
2023-10-30T17:51:53Z  
dc.date.issued
2012-01  
dc.identifier.citation
Mayorga, Luis Segundo; López, María José; Becker, Wayne M.; Molecular thermodynamics for cell biology as taught with boxes; American Society for Cell Biology; Cbeâ—life Sciences Education; 11; 1; 1-2012; 31-38  
dc.identifier.issn
1931-7913  
dc.identifier.uri
http://hdl.handle.net/11336/216444  
dc.description.abstract
Thermodynamic principles are basic to an understanding of the complex fluxes of energy and information required to keep cells alive. These microscopic machines are nonequilibrium systems at the micron scale that are maintained in pseudo-steady-state conditions by very sophisticated processes. Therefore, several nonstandard concepts need to be taught to rationalize why these very ordered systems proliferate actively all over our planet in seeming contradiction to the second law of thermodynamics. We propose a model consisting of boxes with different shapes that contain small balls that are in constant motion due to a stream of air blowing from below. This is a simple macroscopic system that can be easily visualized by students and that can be understood as mimicking the behavior of a set of molecules exchanging energy.With such boxes, the basic concepts of entropy, enthalpy, and free energy can be taught while reinforcing a molecular understanding of the concepts and stressing the stochastic nature of the thermodynamic laws. In addition, time-related concepts, such as reaction rates and activation energy, can be readily visualized. Moreover, the boxes provide an intuitive way to introduce the role in cellular organization of "information" and Maxwell's demons operating under nonequilibrium conditions.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
American Society for Cell Biology  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
TERMODINÁMICA  
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INFORMACIÓN  
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EDUCACIÓN  
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Físico-Química, Ciencia de los Polímeros, Electroquímica  
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Ciencias Químicas  
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CIENCIAS NATURALES Y EXACTAS  
dc.title
Molecular thermodynamics for cell biology as taught with boxes  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-06-05T11:59:01Z  
dc.journal.volume
11  
dc.journal.number
1  
dc.journal.pagination
31-38  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Mayorga, Luis Segundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina  
dc.description.fil
Fil: López, María José. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentina  
dc.description.fil
Fil: Becker, Wayne M.. Department of Botany; Estados Unidos  
dc.journal.title
Cbeâ—life Sciences Education  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.lifescied.org/doi/10.1187/cbe.11-07-0053  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1187/cbe.11-07-0053