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dc.date.available
2023-10-17T18:40:53Z
dc.identifier.citation
Andres, Daniela Sabrina; (2023): Neuronal entropy depends of the level of alertness: data. Consejo Nacional de Investigaciones Científicas y Técnicas. (dataset). http://hdl.handle.net/11336/215244
dc.identifier.uri
http://hdl.handle.net/11336/215244
dc.description.abstract
Microelectrode recordings (MER) obtained from adult rats weighing 250–350 g. assigned to the control group of an experimental Parkinson’s research protocol (Andres et al., 2014). The goal of the experiments was to record the spontaneous activity of the globus pallidus pars interna (GPi, previously called entopeduncular nucleus) under conditions of alertness, environmental silence and blindfoldednes.
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.title
Neuronal entropy depends of the level of alertness: data
dc.type
dataset
dc.date.updated
2023-10-17T18:17:54Z
dc.description.fil
Fil: Andres, Daniela Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Martin. Escuela de Ciencia y Tecnologia. Laboratorio de Neuroingenieria.; Argentina
dc.datacite.PublicationYear
2023
dc.datacite.Creator
Andres, Daniela Sabrina
dc.datacite.affiliation
Consejo Nacional de Investigaciones Científicas y Técnicas
dc.datacite.affiliation
Universidad Nacional de San Martin. Escuela de Ciencia y Tecnologia. Laboratorio de Neuroingenieria.
dc.datacite.affiliation
Consejo Nacional de Investigaciones Científicas y Técnicas
dc.datacite.affiliation
Universidad Nacional de San Martín. Instituto de Altos Estudios Sociales
dc.datacite.publisher
Consejo Nacional de Investigaciones Científicas y Técnicas
dc.datacite.subject
Otras Ciencias Médicas
dc.datacite.subject
Otras Ciencias Médicas
dc.datacite.subject
CIENCIAS MÉDICAS Y DE LA SALUD
dc.datacite.subject
Otros Tópicos Biológicos
dc.datacite.subject
Ciencias Biológicas
dc.datacite.subject
CIENCIAS NATURALES Y EXACTAS
dc.datacite.ContributorType
Other
dc.datacite.ContributorName
Noel, Gabriel David
dc.datacite.date
01/01/2013-31/12/2014
dc.datacite.DateType
Recolectado
dc.datacite.language
eng
dc.datacite.version
1.0
dc.datacite.description
The neuronal recordings used for the present work were originally produced within an experimental Parkinson’s research protocol that followed the partial-lesion model originally described by Sauer and Oertel (1994). The signals analyzed correspond to microelectrode recordings (MER) obtained from adult rats weighing 250–350 g. assigned to the control group of the aforementioned protocol (Andres et al., 2014). The goal of the experiments was to record the spontaneous activity of the globus pallidus pars interna (GPi, previously called entopeduncular nucleus) under conditions of alertness, environmental silence and blindfoldedness. Optimal anesthetic and analgesic medication was used for the recording surgeries, with a three-drug profile consisting of a combination of tramadol, lidocaine and chloral hydrate. Following anesthesia, animals were placed in a restraining device built ad hoc with semi-rigid plastic and a high-quality thermal insulator on the inside. Once the animals were placed, fixed to the stereotactic frame and ready for surgery, we waited until they were completely awake, given the objective was to record spontaneous neuronal activity under complete alertness. The awakening process was monitored periodically with a standardized evaluation of the tail reflex. The purpose of the device was to minimize the animals’ discomfort during the surgery. During the whole procedure animals remained only loosely bound. If they didn’t relax but attempted to move, that was considered an endpoint and the recording surgery was terminated. During the whole surgical procedure, the eyes of the animals were covered and all surgeries were conducted in identical conditions of environmental silence. Recording coordinates fell within the limits defined as the GPi by the last edition of Paxinos and Watson’s (1997) Atlas. Neuronal recordings were obtained using glass- insulated platinum/iridium (Pt/Ir 80/20%) microelectrodes with nominal impedance of 0.8 – 1.2 megohms (mTSPBN-LX1, FHC Inc, Bowdoin, ME, USA). Signals were amplified, conditioned and monitored with an analog oscilloscope, digitized with a dedicated acquisition system (1401 plus, CED) and saved in a computer running Spike 2.0 software. The sampling rate was 20 kHz and total amplification including probe was ×10,000, checked with a built-in calibration signal of 1 mV p-p at the beginning of each experiment.
dc.datacite.DescriptionType
Métodos
dc.datacite.FundingReference
DSA-2011
dc.datacite.FunderName
SOCIETY IN SCIENCE, THE BRANCO-WEISS FELLOWSHIP, ETH
dc.relationtype.isSourceOf
https://ri.conicet.gov.ar/handle/11336/215245
dc.subject.keyword
Actividad neuronal
dc.subject.keyword
Microrregistro neuronal
dc.subject.keyword
Cirugía estereotáctica
dc.subject.keyword
Ratas Sprague-Dawley
dc.datacite.resourceTypeGeneral
dataset
dc.conicet.datoinvestigacionid
13445
dc.datacite.awardTitle
Structure of the Neural Code
dc.datacite.geolocation
Belén de Escobar
dc.datacite.formatedDate
2013-2014
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