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dc.contributor.author
Soleimani, Arshia  
dc.contributor.author
Navarro, Alba  
dc.contributor.author
Liu, Delong  
dc.contributor.author
Herman, Sarah E. M.  
dc.contributor.author
Chuang, Shih Sung  
dc.contributor.author
Slavutsky, Irma Rosa  
dc.contributor.author
Narbaitz, Marina  
dc.contributor.author
Safah, Hana  
dc.contributor.author
Schmieg, John  
dc.contributor.author
Lefante, John  
dc.contributor.author
Roschewski, Mark  
dc.contributor.author
Wilson, Wyndham H.  
dc.contributor.author
Wiestner, Adrian  
dc.contributor.author
Saba, Nakhle S.  
dc.date.available
2023-10-06T14:29:11Z  
dc.date.issued
2022-04  
dc.identifier.citation
Soleimani, Arshia; Navarro, Alba; Liu, Delong; Herman, Sarah E. M.; Chuang, Shih Sung; et al.; CD5-negative mantle cell lymphoma: clinicopathologic features of an indolent variant that confers a survival advantage; Taylor & Francis Ltd; Leukemia and Lymphoma; 63; 4; 4-2022; 911-917  
dc.identifier.issn
1042-8194  
dc.identifier.uri
http://hdl.handle.net/11336/214348  
dc.description.abstract
Conventionally, mantle cell lymphoma (MCL) is an aggressive CD5-positive B-cell malignancy with poor prognosis and limited survival. However, a small subset of patients presents with indolent disease and can be managed on a ‘watch and wait’ approach. CD5-negative MCL has recently been recognized as a more favorable variant of MCL, but its clinical and biological implications remain ill-defined. We performed the most extensive review to-date of all reported cases of CD5-negative MCL and included unpublished cases diagnosed at our institutions to further characterize this disease subset. Based on our analysis of 356 cases of CD5-negative MCL, we conclude that median overall survival exceeds 14 years and is independent of favorable prognostic markers such as leukemic non-nodal disease, absence of SOX11, and low Ki-67.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Taylor & Francis Ltd  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
LYMPHOCYTES  
dc.subject
LYMPHOMA AND HODGKIN DISEASE  
dc.subject
PROGNOSTICATION  
dc.subject.classification
Patología  
dc.subject.classification
Medicina Básica  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
CD5-negative mantle cell lymphoma: clinicopathologic features of an indolent variant that confers a survival advantage  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-07-14T20:22:43Z  
dc.journal.volume
63  
dc.journal.number
4  
dc.journal.pagination
911-917  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Soleimani, Arshia. University of Maryland; Estados Unidos  
dc.description.fil
Fil: Navarro, Alba. Universidad de Barcelona; España  
dc.description.fil
Fil: Liu, Delong. National Institutes of Health; Estados Unidos  
dc.description.fil
Fil: Herman, Sarah E. M.. National Institutes of Health; Estados Unidos  
dc.description.fil
Fil: Chuang, Shih Sung. Chi-Mei Medical Center; China  
dc.description.fil
Fil: Slavutsky, Irma Rosa. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; Argentina  
dc.description.fil
Fil: Narbaitz, Marina. Academia Nacional de Medicina de Buenos Aires. Instituto de Investigaciones Hematológicas "Mariano R. Castex"; Argentina  
dc.description.fil
Fil: Safah, Hana. University of Tulane; Estados Unidos  
dc.description.fil
Fil: Schmieg, John. University of Tulane; Estados Unidos  
dc.description.fil
Fil: Lefante, John. University of Tulane; Estados Unidos  
dc.description.fil
Fil: Roschewski, Mark. National Institutes of Health; Estados Unidos  
dc.description.fil
Fil: Wilson, Wyndham H.. National Institutes of Health; Estados Unidos  
dc.description.fil
Fil: Wiestner, Adrian. National Institutes of Health; Estados Unidos  
dc.description.fil
Fil: Saba, Nakhle S.. University of Tulane; Estados Unidos  
dc.journal.title
Leukemia and Lymphoma  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/abs/10.1080/10428194.2021.2002317  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/10428194.2021.2002317