Artículo
Interaction of Pacemaker Cells and Fibroblasts in the SAN. Another Way of Setting the “Clocks”?
Fecha de publicación:
06/2022
Editorial:
Lippincott Williams
Revista:
Circulation Research
ISSN:
0009-7330
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
A crucial point in heart physiology is to understand the ability of certain heart cells to generate action potentials (AP) independently of an extracardiac stimulus, property known as automatism. Within these automatic cells, the pacemaker cells (PCs) of the sinoauricular node (SAN) are the primary determinants of the cardiac frequency.The most conspicuous characteristic of the AP of the PCs cells is the spontaneous diastolic depolarization (DD), which determines its automaticity and pacemaker activity. In fact, changes in the slope of this spontaneous DD have a major influence on the frequency of AP generation, ultimately establishing the heart rate.
Palabras clave:
ACTION POTENTIALS
,
AUTOMATISM
,
EDITORIALS
,
FIBROBLASTS
,
GLYCOLYSIS
,
PHYSIOLOGY
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(CIC)
Articulos de CENTRO DE INVEST.CARDIOVASCULARES (I)
Articulos de CENTRO DE INVEST.CARDIOVASCULARES (I)
Citación
de Giusti, Verónica Celeste; Villa-Abrille, María Celeste; Aiello, Ernesto Alejandro; Interaction of Pacemaker Cells and Fibroblasts in the SAN. Another Way of Setting the “Clocks”?; Lippincott Williams; Circulation Research; 131; 1; 6-2022; 21-23
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