Artículo
Copper-releasing, boron-containing bioactive glass-based scaffolds coated with alginate for bone tissue engineering
Erol, M. M.; Mouriño, Viviana Silvia Lourdes
; Newby, P.; Chatzistavrou, X.; Roether, Judith A.; Hupa, L.; Boccaccini, Aldo R.
Fecha de publicación:
02/2012
Editorial:
Elsevier
Revista:
Acta Biomaterialia
ISSN:
1742-7061
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The aim of this study was to synthesize and characterize new boron-containing bioactive glass-based scaffolds coated with alginate cross-linked with copper ions. A recently developed bioactive glass powder with nominal composition (wt.%) 65 SiO2, 15 CaO, 18.4 Na2O, 0.1 MgO and 1.5 B2O3 was fabricated as porous scaffolds by the foam replica method. Scaffolds were alginate coated by dipping them in alginate solution. Scanning electron microscopy investigations indicated that the alginate effectively attached on the surface of the three-dimensional scaffolds leading to a homogeneous coating. It was confirmed that the scaffold structure remained amorphous after the sintering process and that the alginate coating improved the scaffold bioactivity and mechanical properties. Copper release studies showed that the alginate-coated scaffolds allowed controlled release of copper ions. The novel copper-releasing composite scaffolds represent promising candidates for bone regeneration.
Palabras clave:
ALGINATE
,
ANTIBACTERIAL
,
BIOACTIVE GLASS
,
CU ION RELEASE
,
SCAFFOLDS
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Licencia
Identificadores
Colecciones
Articulos(OCA HOUSSAY)
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Articulos de OFICINA DE COORDINACION ADMINISTRATIVA HOUSSAY
Citación
Erol, M. M.; Mouriño, Viviana Silvia Lourdes; Newby, P.; Chatzistavrou, X.; Roether, Judith A.; et al.; Copper-releasing, boron-containing bioactive glass-based scaffolds coated with alginate for bone tissue engineering; Elsevier; Acta Biomaterialia; 8; 2; 2-2012; 792-801
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