Artículo
Animal prion diseases: A review of intraspecies transmission
Fecha de publicación:
12/2021
Editorial:
University of Tripoli. Faculty of Veterinary Medicine
Revista:
Open Veterinary Journal
ISSN:
2226-4485
e-ISSN:
2218-6050
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.
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Licencia
Identificadores
Colecciones
Articulos (IPVET)
Articulos de INSTITUTO DE PATOBIOLOGIA VETERINARIA
Articulos de INSTITUTO DE PATOBIOLOGIA VETERINARIA
Citación
Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-723
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