Artículo
SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients
Fecha de publicación:
02/2022
Editorial:
Springer
Revista:
GeroScience
ISSN:
2509-2715
e-ISSN:
2509-2723
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
SARS-CoV-2 is a recently identified coronavirus that causes the current pandemic disease known as COVID-19. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) as a receptor, suggesting that the initial steps of SARS-CoV-2 infection may have an impact on the renin-angiotensin system (RAS). Several processes are influenced by RAS in the brain. The neurological symptoms observed in COVID-19 patients, including reduced olfaction, meningitis, ischemic stroke, cerebral thrombosis, and delirium, could be associated with RAS imbalance. In this review, we focus on the potential role of disturbances in the RAS as a cause for central nervous system sequelae of SARS-CoV-2 infection in elderly patients.
Palabras clave:
CENTRAL NERVOUS SYSTEM
,
COVID-19
,
ELDERLY
,
RENIN-ANGIOTENSIN SYSTEM
,
SARS-COV-2
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(INBIRS)
Articulos de INSTITUTO DE INVESTIGACIONES BIOMEDICAS EN RETROVIRUS Y SIDA
Articulos de INSTITUTO DE INVESTIGACIONES BIOMEDICAS EN RETROVIRUS Y SIDA
Citación
Quarleri, Jorge Fabian; Delpino, María Victoria; SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients; Springer; GeroScience; 44; 2; 2-2022; 547-565
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