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dc.contributor.author
Barrea, Andres Alberto  
dc.contributor.author
Hernandez, Matias Ezequiel  
dc.date.available
2023-09-01T16:44:45Z  
dc.date.issued
2012-03  
dc.identifier.citation
Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-5800  
dc.identifier.uri
http://hdl.handle.net/11336/210200  
dc.description.abstract
In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer).  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Hikari  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
Chemotherapy  
dc.subject
Optimization multiobjetive  
dc.subject
Mathematical Modeling  
dc.subject
Cancer  
dc.subject.classification
Matemática Aplicada  
dc.subject.classification
Matemáticas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Pareto front for chemotherapy scheludes  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-05-30T11:50:42Z  
dc.identifier.eissn
1312-885X  
dc.journal.volume
6  
dc.journal.number
116  
dc.journal.pagination
5789-5800  
dc.journal.pais
Bulgaria  
dc.description.fil
Fil: Barrea, Andres Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina  
dc.description.fil
Fil: Hernandez, Matias Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina  
dc.journal.title
Applied Mathematical Sciences  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.m-hikari.com/ams/ams-2012/ams-113-116-2012/index.html