Mostrar el registro sencillo del ítem

dc.contributor.author
Caceres Ayala, Constanza  
dc.contributor.author
Pautassi, Ricardo Marcos  
dc.contributor.author
Acuña, María José  
dc.contributor.author
Cerpa, Waldo  
dc.contributor.author
Rebolledo, Daniela L.  
dc.date.available
2023-08-15T10:45:45Z  
dc.date.issued
2022-04-07  
dc.identifier.citation
Caceres Ayala, Constanza; Pautassi, Ricardo Marcos; Acuña, María José; Cerpa, Waldo; Rebolledo, Daniela L.; The functional and molecular effects of problematic alcohol consumption on skeletal muscle: a focus on athletic performance; Taylor & Francis Ltd; American Journal of Drug and Alcohol Abuse; 48; 2; 7-4-2022; 133-147  
dc.identifier.issn
0095-2990  
dc.identifier.uri
http://hdl.handle.net/11336/208241  
dc.description.abstract
Background: Chronic alcohol misuse is associated with alcoholic myopathy, characterized by skeletal muscle weakness and atrophy. Moreover, there is evidence that sports-related people seem to exhibit a greater prevalence of problematic alcohol consumption, especially binge drinking (BD), which might not cause alcoholic myopathy but can negatively impact muscle function and amateur and professional athletic performance. Objective: To review the literature concerning the effects of alcohol consumption on skeletal muscle function and structure that can affect muscle performance. Methodology: We examined the currently available literature (PubMed, Google Scholars) to develop a narrative review summarizing the knowledge about the effects of alcohol on skeletal muscle function and exercise performance, obtained from studies in human beings and animal models for problematic alcohol consumption. Results: Exercise- and sport-based studies indicate that alcohol consumption can negatively affect muscle recovery after vigorous exercise, especially in men, while women seem less affected. Clinical studies and pre-clinical laboratory research have led to the knowledge of some of the mechanisms involved in alcohol-related muscle dysfunction, including an imbalance between anabolic and catabolic pathways, reduced regeneration, increased inflammation and fibrosis, and deficiencies in energetic balance and mitochondrial function. These pathological features can appear not only under chronic alcohol misuse but also in other alcohol consumption patterns. Conclusions: Most laboratory-based studies use chronic or acute alcohol exposure, while episodic BD, the most common drinking pattern in amateur and professional athletes, is underrepresented. Nevertheless, alcohol consumption negatively affects skeletal muscle health through different mechanisms, which collectively might contribute to reduced sports performance.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Taylor & Francis Ltd  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
ALCOHOL  
dc.subject
ALCOHOLIC MYOPATHY  
dc.subject
BINGE DRINKING  
dc.subject
MUSCLE PATHOLOGY  
dc.subject
MUSCLE PERFORMANCE  
dc.subject
PROBLEMATIC ALCOHOL CONSUMPTION  
dc.subject.classification
Drogadicción  
dc.subject.classification
Ciencias de la Salud  
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
The functional and molecular effects of problematic alcohol consumption on skeletal muscle: a focus on athletic performance  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-07-04T11:00:41Z  
dc.identifier.eissn
1097-9891  
dc.journal.volume
48  
dc.journal.number
2  
dc.journal.pagination
133-147  
dc.journal.pais
Estados Unidos  
dc.description.fil
Fil: Caceres Ayala, Constanza. Universidad de Magallanes; Chile. Pontificia Universidad Católica de Chile; Chile  
dc.description.fil
Fil: Pautassi, Ricardo Marcos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina. Universidad Nacional de Córdoba. Facultad de Psicología; Argentina  
dc.description.fil
Fil: Acuña, María José. Pontificia Universidad Católica de Chile; Chile  
dc.description.fil
Fil: Cerpa, Waldo. Universidad de Magallanes; Chile. Pontificia Universidad Católica de Chile; Chile  
dc.description.fil
Fil: Rebolledo, Daniela L.. Universidad de Magallanes; Chile. Pontificia Universidad Católica de Chile; Chile  
dc.journal.title
American Journal of Drug and Alcohol Abuse  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.tandfonline.com/doi/full/10.1080/00952990.2022.2041025  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/00952990.2022.2041025