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dc.contributor.author
Retamozo, Ayelen Rocío
dc.contributor.author
Agüero, Facundo Ariel
dc.contributor.author
Fuchs, Alicia Graciela
dc.contributor.author
Maglioco, Andrea Florencia
dc.date.available
2023-08-10T13:58:57Z
dc.date.issued
2021-12
dc.identifier.citation
Retamozo, Ayelen Rocío; Agüero, Facundo Ariel; Fuchs, Alicia Graciela; Maglioco, Andrea Florencia; Serological diagnosis in hydatidosis: Searching standardized antigenic support. Systematic review and meta-analysis; Universidad Abierta Interamericana; Interamerican Journal of Health Sciences; 1; 12-2021; 89-108
dc.identifier.issn
2953-3724
dc.identifier.uri
http://hdl.handle.net/11336/207809
dc.description.abstract
Background: Hydatidosis is a worldwide distributed parasitic zoonosis caused by Echinococcus granulosus s.l. In humans, the diagnosis is based on epidemiological nexus, clinical findings, ultrasound images, and second-line serology. Hydatid fluid is the most widely used source of antigens in serology, but it shows high variability. This review analyzes the diagnostic utility of serology for the diagnosis of hydatidosis, particularly ELISA and Western Blot techniques. Material and methods: Systematic review and meta-analysis of studies with data of diagnostic validity. The reference diagnosis was ultrasound and / or parasitological medical finding. The reproducibility in the studies selection and data extraction was guaranteed, the quality was evaluated according to the QUADAS-2 guide, global results and SROC were obtained under a random effects model in Meta-Disc1.4. Results: Forty-one articles published between 1981 and 2019 were included. Elisa was performed in 33 articles; Western Blot was performed in 14 articles and some of the articles included both techniques. The included articles presented high heterogeneity. The SROC parameters were AUC = 0.9511 and Q=0.8919 for ELISA and AUC=0.9693 and Q = 0.9186 for Western Blot. Conclusion: ELISA and Western Blot have good diagnostic accuracy.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Universidad Abierta Interamericana
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-sa/2.5/ar/
dc.subject
ECHINOCOCUS GRANULOSUS
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SEROLOGY
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HUMAN
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DIAGNOSTIC OF HYDATIDOSIS
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HYDATID CYST
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Parasitología
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Ciencias de la Salud
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Serological diagnosis in hydatidosis: Searching standardized antigenic support. Systematic review and meta-analysis
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-08-09T12:49:48Z
dc.journal.number
1
dc.journal.pagination
89-108
dc.journal.pais
Argentina
dc.journal.ciudad
Ciudad Autónoma de Buenos Aires
dc.description.fil
Fil: Retamozo, Ayelen Rocío. Universidad Abierta Interamericana; Argentina
dc.description.fil
Fil: Agüero, Facundo Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Abierta Interamericana. Facultad de Medicina. Centro de Altos Estudios en Ciencias de la Salud; Argentina
dc.description.fil
Fil: Fuchs, Alicia Graciela. Universidad Abierta Interamericana. Facultad de Medicina. Centro de Altos Estudios en Ciencias de la Salud; Argentina. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorio e Instituto de Salud “Dr. C. G. Malbrán”. Instituto Nacional de Parasitología "Dr. Mario Fatala Chaben”; Argentina
dc.description.fil
Fil: Maglioco, Andrea Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Abierta Interamericana. Facultad de Medicina. Centro de Altos Estudios en Ciencias de la Salud; Argentina
dc.journal.title
Interamerican Journal of Health Sciences
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://ijhsc.com/journal/article/view/41
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.59471/ijhsc202141
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