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dc.contributor.author
Menkhorst, Ellen  
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Than, Nandor Gabor  
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Jeschke, Udo  
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Barrientos, Gabriela Laura  
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Szereday, Laszlo  
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Dveksler, Gabriela  
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Blois, Sandra M.  
dc.date.available
2023-08-09T14:48:22Z  
dc.date.issued
2021-12  
dc.identifier.citation
Menkhorst, Ellen; Than, Nandor Gabor; Jeschke, Udo; Barrientos, Gabriela Laura; Szereday, Laszlo; et al.; Medawar’s PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation; Frontiers Media; Frontiers in Immunology; 12; 12-2021; 1-18  
dc.identifier.issn
1664-3224  
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http://hdl.handle.net/11336/207611  
dc.description.abstract
Lectin-glycan interactions, in particular those mediated by the galectin family, regulate many processes required for a successful pregnancy. Over the past decades, increasing evidence gathered from in vitro and in vivo experiments indicate that members of the galectin family specifically bind to both intracellular and membrane bound carbohydrate ligands regulating angiogenesis, immune-cell adaptations required to tolerate the fetal semi-allograft and mammalian embryogenesis. Therefore, galectins play important roles in fetal development and placentation contributing to maternal and fetal health. This review discusses the expression and role of galectins during the course of pregnancy, with an emphasis on maternal immune adaptions and galectin-glycan interactions uncovered in the recent years. In addition, we summarize the galectin fingerprints associated with pathological gestation with particular focus on preeclampsia.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Frontiers Media  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
GALECTINS  
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GLYCOIMMUNOLOGY  
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PLACENTA  
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PREGNANCY  
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PREGNANCY SPECIFIC PROTEINS  
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Inmunología  
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Medicina Básica  
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CIENCIAS MÉDICAS Y DE LA SALUD  
dc.title
Medawar’s PostEra: Galectins Emerged as Key Players During Fetal-Maternal Glycoimmune Adaptation  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-08-09T12:50:38Z  
dc.journal.volume
12  
dc.journal.pagination
1-18  
dc.journal.pais
Suiza  
dc.description.fil
Fil: Menkhorst, Ellen. University of Melbourne; Australia  
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Fil: Than, Nandor Gabor. Research Centre for Natural Sciences; Hungría  
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Fil: Jeschke, Udo. University Hospital Augsburg; Alemania  
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Fil: Barrientos, Gabriela Laura. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Aleman; Argentina  
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Fil: Szereday, Laszlo. University of Pecs; Hungría  
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Fil: Dveksler, Gabriela. No especifíca;  
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Fil: Blois, Sandra M.. University Medical Center Hamburg-Eppendorf; Alemania  
dc.journal.title
Frontiers in Immunology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fimmu.2021.784473