Artículo
Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells
Aarntzen, Erik H. J. G.; Srinivas, Mangala; Bonetto, Fernando Jose
; Cruz, Luis J.; Verdijk, Pauline; Schreibelt, Gerty; Van de Rakt, Mandy; Lesterhuis, W. Joost; Van Riel, Maichel; Punt, Cornelius J. A.; Adema, Gosse J.; Heerschap, Arend; Figdor, Carl G.; Oyen, Wim J.; de Vries, I. Jolanda M.
Fecha de publicación:
15/03/2013
Editorial:
American Association for Cancer Research
Revista:
Clinical Cancer Research
ISSN:
1078-0432
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Anti-cancer dendritic cell (DC) vaccines require the DC to relocate to lymph nodes (LN) to trigger immune responses. However, these migration rates are typically very poor. Improving the targeting of ex vivo generated DC to LN might increase vaccine efficacy and reduce costs. We investigated DC migration in vivo in humans in different conditions.
Palabras clave:
Dendritic Cells
,
19f Magnetic Resonance Imaging
,
Migration
,
Immunotherapy
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Articulos(INTEC)
Articulos de INST.DE DES.TECNOL.PARA LA IND.QUIMICA (I)
Articulos de INST.DE DES.TECNOL.PARA LA IND.QUIMICA (I)
Citación
Aarntzen, Erik H. J. G.; Srinivas, Mangala; Bonetto, Fernando Jose; Cruz, Luis J.; Verdijk, Pauline; et al.; Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells; American Association for Cancer Research; Clinical Cancer Research; 19; 15-3-2013; 1525-1533
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