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dc.contributor.author
Pautassi, Ricardo Marcos
dc.contributor.author
Fabio, Maria Carolina
dc.date.available
2023-08-03T15:12:34Z
dc.date.issued
2022-10-13
dc.identifier.citation
Pautassi, Ricardo Marcos; Fabio, Maria Carolina; A double-hit model reveals individual and synergic consequences of prenatal and adolescent postnatal ethanol exposure; Wiley Blackwell Publishing, Inc; Alcoholism: Clinical And Experimental Research; 46; 12; 13-10-2022; 2160-2162
dc.identifier.issn
0145-6008
dc.identifier.uri
http://hdl.handle.net/11336/206854
dc.description.abstract
Prenatal alcohol exposure is highly prevalent worldwide. InArgentina, Lichtenberger et al. (2020) reported that 2 out of 10women reported drinking during pregnancy. Reports from the US,in turn, suggest that around 5% of pregnant women endorse bingedrinking (i.e., the ingestion of four standard drinks in a single andusually brief drinking episode) sometime at pregnancy (Popovaet al., 2017). Prenatal EtOH exposure (PEE) is associated with amyriad of consequences, namely neuroanatomical alterations thattranslate into neuropsychological deficits and mental disorders,including attentional deficits and greater likelihood of being diagnosed with autism spectrum disorder, mental retardation (Geier &Geier, 2022) or with a group of conditions known as fetal alcoholspectrum disorders (FASDs) (Palmeter et al., 2021). Other studies suggest that PEE is associated with lingering changes in EtOHsensitivity or acceptance during infancy or adolescence, whenvoluntary EtOH drinking begins and escalates. Illustrating this, aseminal study indicated that PEE was the best predictor of adolescent involvement with EtOH, over and beyond relevant variables,such as nicotine exposure or a positive family history of alcohol usedisorder (Baer et al., 2003). In our lab, in turn, we have shown thatrats with a history of PEE exhibit, when compared to control counterparts, heightened EtOH intake (Fabio et al., 2013) and greaterEtOH-induced conditioned place preference (Pautassi et al., 2012),a measure of conditioned reward.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Wiley Blackwell Publishing, Inc
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights
Atribución-NoComercial-CompartirIgual 2.5 Argentina (CC BY-NC-SA 2.5 AR)
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
COMMENTARY
dc.subject
POSTNATAL ETHANOL
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PRENATAL ETHANOL
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THIRD TRIMESTER
dc.subject.classification
Drogadicción
dc.subject.classification
Ciencias de la Salud
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
A double-hit model reveals individual and synergic consequences of prenatal and adolescent postnatal ethanol exposure
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-07-04T10:53:00Z
dc.identifier.eissn
1530-0277
dc.journal.volume
46
dc.journal.number
12
dc.journal.pagination
2160-2162
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Pautassi, Ricardo Marcos. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
dc.description.fil
Fil: Fabio, Maria Carolina. Universidad Nacional de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina
dc.journal.title
Alcoholism: Clinical And Experimental Research
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/acer.14957
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1111/acer.14957
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