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dc.contributor.author
Zanlungo, Silvana
dc.contributor.author
Enrich, Carlos
dc.contributor.author
Gerke, Volker
dc.contributor.author
Eden, Emily R.
dc.contributor.author
Colombo, Maria Isabel
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dc.date.available
2023-07-26T17:48:19Z
dc.date.issued
2022-11
dc.identifier.citation
Zanlungo, Silvana; Enrich, Carlos; Gerke, Volker; Eden, Emily R.; Colombo, Maria Isabel; Cell compartments and intracellular trafficking of lipids and proteins: Impact on biomedicine; Frontiers Media; Frontiers in Cell and Developmental Biology; 10; 11-2022; 1-4
dc.identifier.issn
2296-634X
dc.identifier.uri
http://hdl.handle.net/11336/205665
dc.description.abstract
Endocytosis and cell compartments define eukaryotic cells and evolution has sculpted a complex subset of intracellular structures to arrange the modern cell. This process has been long, implicating each single organelle to eventually develop a functional consortium where spatio-temporal distribution becomes essential. Because of this intrinsic extreme complexity minor alterations must be repaired, replaced, or undergo reorganization. This is also important when it comes to biochemical processes within and between cellular compartments developing a new concept that implicates cell compartments not to function as individual and isolated entities, but as a dynamic and regulated ensemble facilitating the intracellular trafficking of lipids and proteins. The diverse intracellular compartments contribute to a global cell homeostasis and alterations provide new insights relevant for a number of human diseases and offer opportunities for the design of innovative therapies and treatments.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Frontiers Media
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dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
CHOLESTEROL
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DISEASE MODELS
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ENDOSOMES
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LIPID DROPLETS
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LYSOSOMAL STORAGE DISEASES
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LYSOSOME-RELATED ORGANELLES
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LYSOSOMES
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MEMBRANE CONTACT SITES
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Biología Celular, Microbiología
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dc.subject.classification
Ciencias Biológicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Cell compartments and intracellular trafficking of lipids and proteins: Impact on biomedicine
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-07-18T14:21:18Z
dc.journal.volume
10
dc.journal.pagination
1-4
dc.journal.pais
Suiza
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dc.description.fil
Fil: Zanlungo, Silvana. Universidad Católica de Chile; Chile
dc.description.fil
Fil: Enrich, Carlos. Universidad de Barcelona; España
dc.description.fil
Fil: Gerke, Volker. Westfälische Wilhelms Universität; Alemania
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Fil: Eden, Emily R.. UCL Institute of Ophthalmology; Reino Unido
dc.description.fil
Fil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
dc.journal.title
Frontiers in Cell and Developmental Biology
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fcell.2022.1087214/full
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fcell.2022.1087214
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