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dc.contributor.author Bogsan, Cristina Stewart Bittencourt
dc.contributor.author Ferreira, Luis
dc.contributor.author Maldonado Galdeano, María Carolina
dc.contributor.author Perdigon, Gabriela del Valle
dc.contributor.author Almeida, Sandro Rogério
dc.contributor.author Oliveira, Maricê Nogueira de
dc.date.available 2017-07-14T16:59:14Z
dc.date.issued 2014-06
dc.identifier.citation Bogsan, Cristina Stewart Bittencourt; Ferreira, Luis; Maldonado Galdeano, María Carolina; Perdigon, Gabriela del Valle; Almeida, Sandro Rogério; et al.; Fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019: Technological approach determines the probiotic modulation of mucosal cellular immunity; Elsevier Science; Food Research International; 64; 6-2014; 283-288
dc.identifier.issn 0963-9969
dc.identifier.uri http://hdl.handle.net/11336/20559
dc.description.abstract Functional foods are important sources of probiotic delivery, mainly by fermentedmilk products. The physiological benefits attributed to bifido bacteria are their abilities to interfere with the adhesion of pathogenic species to surfaces of intestinal cells, and to enhance the host's immune function through their metabolic activities. However, the effects of a technological approach ? fermentation or addition of probiotic in milk, and its efficacy in health are rarely taken into consideration. Hence, fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019 were administered to BALB/c mice for 14 days. After that, the architecture of the gut was histologically investigated, and the related immune cells were examined by flow cytometry and immunofluorescence. Increase in mucus and cellularity production, changes in immune pattern and preservation of mucosal epithelia in health BALB/c mice were observed only in the fermentedmilk group. This suggested that changes in functionality of bifidobacteria and/or themetabolites produced by the fermentation process are the keys to improving beneficial effects in the host of the gut mucosa.
dc.format application/pdf
dc.language.iso eng
dc.publisher Elsevier Science
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject FERMENTED
dc.subject MILK
dc.subject IMMUNOMODULATION
dc.subject B1 CELLS
dc.subject MATRIX-PROBIOTIC-MUCOSA INTERACTION
dc.subject BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS HN019
dc.subject.classification Inmunología
dc.subject.classification Medicina Básica
dc.subject.classification CIENCIAS MÉDICAS Y DE LA SALUD
dc.title Fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019: Technological approach determines the probiotic modulation of mucosal cellular immunity
dc.type info:eu-repo/semantics/article
dc.type info:ar-repo/semantics/artículo
dc.type info:eu-repo/semantics/publishedVersion
dc.date.updated 2017-07-03T20:14:19Z
dc.identifier.eissn 1873-7145
dc.journal.volume 64
dc.journal.pagination 283-288
dc.journal.pais Canadá
dc.journal.ciudad Otawa
dc.description.fil Fil: Bogsan, Cristina Stewart Bittencourt. Universidade de Sao Paulo; Brasil
dc.description.fil Fil: Ferreira, Luis. Universidade de Sao Paulo; Brasil
dc.description.fil Fil: Maldonado Galdeano, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentina
dc.description.fil Fil: Perdigon, Gabriela del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentina
dc.description.fil Fil: Almeida, Sandro Rogério. Universidade de Sao Paulo; Brasil
dc.description.fil Fil: Oliveira, Maricê Nogueira de. Universidade de Sao Paulo; Brasil
dc.journal.title Food Research International
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.foodres.2014.05.036
dc.relation.alternativeid info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0963996914003512


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info:eu-repo/semantics/restrictedAccess Excepto donde se diga explícitamente, este item se publica bajo la siguiente descripción: Creative Commons Attribution-NonCommercial-ShareAlike 2.5 Unported (CC BY-NC-SA 2.5)