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dc.contributor.author
Bogsan, Cristina Stewart Bittencourt
dc.contributor.author
Ferreira, Luis
dc.contributor.author
Maldonado Galdeano, María Carolina
dc.contributor.author
Perdigon, Gabriela del Valle
dc.contributor.author
Almeida, Sandro Rogério
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Oliveira, Maricê Nogueira de
dc.date.available
2017-07-14T16:59:14Z
dc.date.issued
2014-06
dc.identifier.citation
Bogsan, Cristina Stewart Bittencourt; Ferreira, Luis; Maldonado Galdeano, María Carolina; Perdigon, Gabriela del Valle; Almeida, Sandro Rogério; et al.; Fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019: Technological approach determines the probiotic modulation of mucosal cellular immunity; Elsevier Science; Food Research International; 64; 6-2014; 283-288
dc.identifier.issn
0963-9969
dc.identifier.uri
http://hdl.handle.net/11336/20559
dc.description.abstract
Functional foods are important sources of probiotic delivery, mainly by fermentedmilk products. The physiological benefits attributed to bifido bacteria are their abilities to interfere with the adhesion of pathogenic species to surfaces of intestinal cells, and to enhance the host's immune function through their metabolic activities. However, the effects of a technological approach ? fermentation or addition of probiotic in milk, and its efficacy in health are rarely taken into consideration. Hence, fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019 were administered to BALB/c mice for 14 days. After that, the architecture of the gut was histologically investigated, and the related immune cells were examined by flow cytometry and immunofluorescence. Increase in mucus and cellularity production, changes in immune pattern and preservation of mucosal epithelia in health BALB/c mice were observed only in the fermentedmilk group. This suggested that changes in functionality of bifidobacteria and/or themetabolites produced by the fermentation process are the keys to improving beneficial effects in the host of the gut mucosa.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Fermented
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Milk
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Immunomodulation
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B1 Cells
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Matrix-Probiotic-Mucosa Interaction
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Bifidobacterium Animalis Subsp. Lactis Hn019
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Inmunología
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Medicina Básica
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CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Fermented or unfermented milk using Bifidobacterium animalis subsp. lactis HN019: Technological approach determines the probiotic modulation of mucosal cellular immunity
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-07-03T20:14:19Z
dc.identifier.eissn
1873-7145
dc.journal.volume
64
dc.journal.pagination
283-288
dc.journal.pais
Canadá
dc.journal.ciudad
Otawa
dc.description.fil
Fil: Bogsan, Cristina Stewart Bittencourt. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Ferreira, Luis. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Maldonado Galdeano, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentina
dc.description.fil
Fil: Perdigon, Gabriela del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentina
dc.description.fil
Fil: Almeida, Sandro Rogério. Universidade de Sao Paulo; Brasil
dc.description.fil
Fil: Oliveira, Maricê Nogueira de. Universidade de Sao Paulo; Brasil
dc.journal.title
Food Research International
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.foodres.2014.05.036
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0963996914003512


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