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dc.contributor.author
Piloni, Natacha Estefanía  
dc.contributor.author
Puntarulo, Susana Ángela  
dc.contributor.other
Kumar Chittoria, Ravi  
dc.date.available
2023-07-19T16:09:37Z  
dc.date.issued
2022  
dc.identifier.citation
Piloni, Natacha Estefanía; Puntarulo, Susana Ángela; Effect of Fe overload on ascorbyl radical steady state concentration in rat brain; B P International; 4; 2022; 1-17  
dc.identifier.isbn
978-93-5547-448-3  
dc.identifier.uri
http://hdl.handle.net/11336/204474  
dc.description.abstract
The one-electron oxidation of ascorbate produces the ascorbyl radical (A), that has beenproposed as a marker of oxidative stress either in vitro, or in vivo in numerous systems. Theapplication of a simple kinetic analysis allowed us to estimate the steady state concentration of A.These data were successfully compared to experimental values obtained using ElectronParamagnetic Resonance (EPR) in rat brain under physiological conditions and the response tostress due to sub-chronic Fe overload. The main objective of this chapter is to further explore theinformation presented in a previously published manuscript employing a simple kinetic modeldeveloped to estimate A steady state concentration to other Fe-dependent oxidative conditions inrat brain.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
B P International  
dc.rights
info:eu-repo/semantics/restrictedAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/  
dc.subject
ASCORBYL RADICAL  
dc.subject
BRAIN  
dc.subject
IRON OVERLOAD  
dc.subject
KINETIC MODEL  
dc.subject.classification
Bioquímica y Biología Molecular  
dc.subject.classification
Ciencias Biológicas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Effect of Fe overload on ascorbyl radical steady state concentration in rat brain  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.type
info:eu-repo/semantics/bookPart  
dc.type
info:ar-repo/semantics/parte de libro  
dc.date.updated
2023-07-05T12:21:29Z  
dc.journal.volume
4  
dc.journal.pagination
1-17  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Piloni, Natacha Estefanía. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.description.fil
Fil: Puntarulo, Susana Ángela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.bookpi.org/bookstore/product/issues-and-developments-in-medicine-and-medical-research-vol-4/  
dc.conicet.paginas
146  
dc.source.titulo
Issues and Developments in Medicine and Medical Research  

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