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dc.contributor.author
Rial, Ramón
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dc.contributor.author
Liu, Zhen
dc.contributor.author
Messina, Paula Verónica
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dc.contributor.author
Ruso, Juan Manuel
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dc.date.available
2023-07-19T02:49:15Z
dc.date.issued
2022-06
dc.identifier.citation
Rial, Ramón; Liu, Zhen; Messina, Paula Verónica; Ruso, Juan Manuel; Role of nanostructured materials in hard tissue engineering; Elsevier Science; Advances In Colloid And Interface Science; 304; 6-2022; 1-16
dc.identifier.issn
0001-8686
dc.identifier.uri
http://hdl.handle.net/11336/204362
dc.description.abstract
The rise in the use of biomaterials in bone regeneration in the last decade has exponentially multiplied the number of publications, methods, and approaches to improve and optimize their functionalities and applications. In particular, biomimetic strategies based on the self-assembly of molecules to design, create and characterize nanostructured materials have played a very relevant role. We address this idea on four different but related points: self-setting bone cements based on calcium phosphate, as stable tissue support and regeneration induction; metallic prosthesis coatings for cell adhesion optimization and prevention of inflammatory response exacerbation; bio-adhesive hybrid materials as multiple drug delivery localized platforms and finally bio-inks. The effect of the physical, chemical, and biological properties of the newest biomedical devices on their bone tissue regenerative capacity are summarized, described, and analyzed in detail. The roles of experimental conditions, characterization methods and synthesis routes are emphasized. Finally, the future opportunities and challenges of nanostructured biomaterials with their advantages and shortcomings are proposed in order to forecast the future directions of this field of research.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Elsevier Science
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
HARD TISSUE
dc.subject
BIOCERAMICS
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CALCIUM PHOSPHATE CEMENTS
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METALLIC IMPLANTS
dc.subject.classification
Nano-materiales
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dc.subject.classification
Nanotecnología
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dc.subject.classification
INGENIERÍAS Y TECNOLOGÍAS
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dc.title
Role of nanostructured materials in hard tissue engineering
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-07-06T21:47:13Z
dc.journal.volume
304
dc.journal.pagination
1-16
dc.journal.pais
Países Bajos
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dc.journal.ciudad
Amsterdam
dc.description.fil
Fil: Rial, Ramón. Universidad de Santiago de Compostela; España
dc.description.fil
Fil: Liu, Zhen. Frostburg State University; Estados Unidos
dc.description.fil
Fil: Messina, Paula Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
dc.description.fil
Fil: Ruso, Juan Manuel. Universidad de Santiago de Compostela; España
dc.journal.title
Advances In Colloid And Interface Science
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.cis.2022.102682
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0001868622000847
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