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dc.contributor.author
Benedini, Luciano Alejandro
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dc.date.available
2023-07-13T14:35:50Z
dc.date.issued
2022-02
dc.identifier.citation
Benedini, Luciano Alejandro; Advanced protein drugs and formulations; Bentham Science Publishers; Current Protein and Peptide Science; 23; 1; 2-2022; 2-5
dc.identifier.issn
1875-5550
dc.identifier.uri
http://hdl.handle.net/11336/203786
dc.description.abstract
Previously, the application of proteins was uncommon as therapeutically active molecules. Some of the first applications of proteins as drugs have been insulin and vaccines for overcoming a physiological deficiency and the prevention of diseases, respectively. Nowadays, proteins have many applications, not only as drugs but also as drug delivery systems to be administered by different routes. Due to their nature, the behavior of proteins varies while the conditions of the environment are modified. For this reason, it is necessary to study their behavior for predicting the correct manufacturing, storing, or combination with other possible molecules in a formulation or into the body. The application of techniques for predicting the behavior of proteins in different environments has led to associating this type of behavior into the body with the occurrence of diseases, such as celiac disease or Alzheimer's disease. Thus, this work shows an overview of the main types of proteins applied as active therapeutically molecules, proteins-based drug delivery systems, and techniques for predicting their stability into the primary storing container and the body.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Bentham Science Publishers
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dc.rights
info:eu-repo/semantics/restrictedAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
PROTEINS
dc.subject
ACTIVE THERAPEUTIC AGENTS
dc.subject
CLASSIFICATION
dc.subject.classification
Otras Ciencias Químicas
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dc.subject.classification
Ciencias Químicas
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dc.subject.classification
CIENCIAS NATURALES Y EXACTAS
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dc.title
Advanced protein drugs and formulations
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-07-06T21:56:13Z
dc.identifier.eissn
1389-2037
dc.journal.volume
23
dc.journal.number
1
dc.journal.pagination
2-5
dc.journal.pais
Estados Unidos
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dc.journal.ciudad
Oak Park
dc.description.fil
Fil: Benedini, Luciano Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
dc.journal.title
Current Protein and Peptide Science
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dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/1389203722666211210115040
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.eurekaselect.com/public/article/119338
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