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dc.contributor.author
Ruiz Brunner, María de Las Mercedes
dc.contributor.author
Cuestas, Eduardo
dc.contributor.author
Heinen, Florian
dc.contributor.author
Schroeder, Andreas Sebastian
dc.date.available
2023-07-07T17:57:53Z
dc.date.issued
2022-02-03
dc.identifier.citation
Ruiz Brunner, María de Las Mercedes; Cuestas, Eduardo; Heinen, Florian; Schroeder, Andreas Sebastian; Growth in infants, children and adolescents with unilateral and bilateral cerebral palsy; Nature Publishing Group; Scientific Reports; 12; 1; 3-2-2022; 1-9
dc.identifier.uri
http://hdl.handle.net/11336/202746
dc.description.abstract
To compare growth patterns during infancy, childhood and adolescence in children with unilateral and bilateral cerebral palsy (CP) phenotype and to assess the association with gross motor impairment, dysphagia and gestational age. We retrospectively studied 389 children with CP from a single center population in Munich, Germany. 1536 measurements of height and weight were tabulated and z-scored from 6 to 180 months of age. Generalized linear mixed model were used to examine the association between growth, GMFCS, dysphagia and gestational age by CP phenotype. Children with unilateral CP tend to grow similarly to their typically developed peers. In the main effect model, bilateral CP phenotype was significantly associated with decreased mean z-scores for height (β [95% CI] − 0.953 [− 1.145, − 0.761], p < 0.001), weight (− 0.999 [− 1.176, − 0.807], p < 0.001) and BMI (β [95% CI] − 0.437 [− 0.799, − 0.075]), compared with unilateral CP phenotype. This association remained significant in the interaction models. The height-for-age z-scores, weight-for-age decreased z-scores and BMI-for-age z-scores of children with bilateral CP and GMFCS III–V or dysphagia decreased more significantly than those of children with unilateral CP. Preterm birth was not significantly associated with decreased growth in height, weight and BMI. Reduced growth in children with bilateral CP was strongly associated with moderate to severe impairment in gross motor function (GMFCS III–V) and dysphagia.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Nature Publishing Group
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by/2.5/ar/
dc.subject
DISABILITY
dc.subject
CEREBRAL PALSY
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GROWTH
dc.subject
WEIGHT
dc.subject.classification
Pediatría
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Medicina Clínica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Growth in infants, children and adolescents with unilateral and bilateral cerebral palsy
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2023-07-03T15:37:02Z
dc.identifier.eissn
2045-2322
dc.journal.volume
12
dc.journal.number
1
dc.journal.pagination
1-9
dc.journal.pais
Reino Unido
dc.journal.ciudad
Londres
dc.description.fil
Fil: Ruiz Brunner, María de Las Mercedes. Hauner Children’s Hospital; Alemania. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina
dc.description.fil
Fil: Cuestas, Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; Argentina. Gobierno de la Provincia de Cordoba. Hospital Misericordia Nuevo Siglo; Argentina
dc.description.fil
Fil: Heinen, Florian. Hauner Children’s Hospital; Alemania
dc.description.fil
Fil: Schroeder, Andreas Sebastian. Hauner Children’s Hospital; Alemania
dc.journal.title
Scientific Reports
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1038/s41598-022-05267-y
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41598-022-05267-y
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