Design of smart nanodevices based on N-vinyl caprolactam nanogels for photosensitizers

Abstract

Smart PVCL-based nanogels for photosensitizers were prepared following the thermo precipitation methodology. PVCL-based imprinted and non-imprinted NGs are reported with different percentages of N,N′-methylenebisacrylamide (BIS) as crosslinker agent. Zn(II)phthalocyanine (ZnPc) is employed as a model photosensitizer and incorporated as a template molecule for imprinted NGs or it loads post-synthesis for non-imprinted NGs. In order to analyze the chemical structure, NGs were characterized using infrared microscopy. Hydrodynamic diameter was determined by dynamic light scattering. The phase transition temperature was measured by UV–vis spectroscopy. The phase transition temperature and Dh values were regulated by the percentage of crosslinker and the presence of the photosensitizer as a template or post-synthesis load. In all cases, the yields were acceptable and the smart nanodevices were stable.