Artículo
Non-linear susceptibility to interferences in declarative memory formation
Moyano, Malen Daiana
; Carbonari, Giulia; Bonilla, Matías
; Pedreira, Maria Eugenia
; Brusco, Luis Ignacio
; Kaczer, Laura
; Forcato, Cecilia
Fecha de publicación:
06/2022
Editorial:
Public Library of Science
Revista:
Plos One
ISSN:
1932-6203
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
After encoding, memories go through a labile state followed by a stabilization process known as consolidation. Once consolidated they can enter a new labile state after the presentation of a reminder of the original memory, followed by a period of re-stabilization (reconsolidation). During these periods of lability the memory traces can be modified. Currently, some studies show a rapid stabilization after 30 min, while others show that stabilization occurs after longer periods (e.g. > 6 h). Here we investigate the effect of an interference treatment on declarative memory consolidation, comparing distinct time intervals after acquisition. On day 1, participants learned a list of non- syllable pairs (List 1). 5 min, 30 min, 3 h or 8 h later, they received an interference list (List 2) that acted as an amnesic agent. On day 2 (48 h after training) participants had to recall List 1 first, followed by List 2. We found that the List 1 memory was susceptible to interference when List 2 was administered 5 min or 3 h after learning but not when it was administered 30 min or 8 h after. We propose the possibility that this rapid memory protection could be induced by a fast and transient neocortical integration. Our results open a discussion about the contribution of molecular and systemic aspects to memory consolidation.
Palabras clave:
CONSOLIDATION
,
LABILIZATION
,
INTERFERENCE
,
DECLARATIVE MEMORY
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Articulos(IFIBYNE)
Articulos de INST.DE FISIOL., BIOL.MOLECULAR Y NEUROCIENCIAS
Articulos de INST.DE FISIOL., BIOL.MOLECULAR Y NEUROCIENCIAS
Articulos(SEDE CENTRAL)
Articulos de SEDE CENTRAL
Articulos de SEDE CENTRAL
Citación
Moyano, Malen Daiana; Carbonari, Giulia; Bonilla, Matías; Pedreira, Maria Eugenia; Brusco, Luis Ignacio; et al.; Non-linear susceptibility to interferences in declarative memory formation; Public Library of Science; Plos One; 17; 6-2022; 1-16
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