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dc.contributor.author
Rodríguez Seguí, Santiago Andrés
dc.contributor.author
Bessa, José
dc.date.available
2017-07-11T19:13:03Z
dc.date.issued
2015
dc.identifier.citation
Rodríguez Seguí, Santiago Andrés; Bessa, José; Gatekeepers of pancreas: TEAD and YAP; Impact journals; Oncotarget; 6; -1-2015; 15736-15737
dc.identifier.issn
1949-2553
dc.identifier.uri
http://hdl.handle.net/11336/20137
dc.description.abstract
The pancreas hosts some of the most debilitating and deadly diseases, including pancreatic cancer and diabetes mellitus. In autoimmune diabetes, for example, there is a massive destruction of the insulin producing cells of the pancreas. Pancreatic developmental defects can also result in a deficit of this cell type. To revert these important pancreatic diseases, researchers are currently trying to artificially generate insulin producing beta-cells for implantation and, in this way, suppress insulin administration [1]. However, to derive cells that function properly it is necessary to understand in depth the instructions that our body uses to produce them during fetal development. On the other hand, regarding pancreatic cancer, it is known that tumor cells very often recover characteristics similar to those of embryonic cells [2]. These are clear examples of the relevance to understand the identity of pancreatic progenitor cells.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Impact journals
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
Tead
dc.subject
Yap
dc.subject
Pancreas Development
dc.subject
Enhancer
dc.subject.classification
Bioquímica y Biología Molecular
dc.subject.classification
Medicina Básica
dc.subject.classification
CIENCIAS MÉDICAS Y DE LA SALUD
dc.title
Gatekeepers of pancreas: TEAD and YAP
dc.type
info:eu-repo/semantics/article
dc.type
info:ar-repo/semantics/artículo
dc.type
info:eu-repo/semantics/publishedVersion
dc.date.updated
2017-07-11T13:25:52Z
dc.journal.volume
6
dc.journal.pagination
15736-15737
dc.journal.pais
Estados Unidos
dc.description.fil
Fil: Rodríguez Seguí, Santiago Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
dc.description.fil
Fil: Bessa, José. Universidad de Porto; Portugal
dc.journal.title
Oncotarget
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.18632/oncotarget.4607
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=4607


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