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dc.contributor.author
Saracho, Hayde
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Marcelino, Virginia
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Kurth, Daniel German
dc.date.available
2023-06-22T12:33:05Z
dc.date.issued
2022
dc.identifier.citation
Identification of immune systems with potential biotechnological application in bacteria of the genus Acinetobacter; LVIII Annual Meeting of the Argentine Society for Biochemistry and Molecular Biology Research; Mendoza; Argentina; 2022; 330-331
dc.identifier.uri
http://hdl.handle.net/11336/201116
dc.description.abstract
Bacteria and archaea are constantly exposed to the rampant invasion of phages or plasmids, generically known as mobile genetic elements (MGEs). In response, they have evolved diverse, complex defense systems that limit the intrusion of these foreign elements.Many new types of defense systems have recently been discovered by studying the genomic 'dark matter' of defense islands using a blame-by-association approach: uncharacterized genes that commonly reside alongside genes from known phage defense systems. they often encode new defense systems. As more genomic data is deposited in sequence databases, so are renewed efforts to comprehensively identify and characterize known defense systems.We propose to evaluate the heterogeneity of two recently developed tools: Prokaryotic Antiviral Defense LOCator (PADLOC) and DefenseFinder of in silico prediction of phage defense systems from NCBI genomes.From a Unix command line we used the rsync program and downloaded from RefSeq release 212, 8468 genomes of bacteria of the genus Acinetobacter. We make the predictions locally and compare them with each other.We believe that the integration of PADLOC and DefenseFinder is necessary since both tools are valuable for the identification and future characterization of defense systems against phages in bacteria of the genus Acinetobacter. No single best approach was identified. The definition of the “defense islands” on each genome will provide new regions to identify potentially new systems.
dc.format
application/pdf
dc.language.iso
eng
dc.publisher
Sociedad Argentina de Investigaciones en Bioquímica y Biología Molecular
dc.rights
info:eu-repo/semantics/openAccess
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subject
ACINETOBACTER
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BACTERIAL IMMUNITY
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GENOMICS
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MOBILE GENETIC ELEMENTS
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Biología Celular, Microbiología
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
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Bioquímica y Biología Molecular
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Ciencias Biológicas
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CIENCIAS NATURALES Y EXACTAS
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Ciencias de la Información y Bioinformática
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Ciencias de la Computación e Información
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CIENCIAS NATURALES Y EXACTAS
dc.title
Identification of immune systems with potential biotechnological application in bacteria of the genus Acinetobacter
dc.type
info:eu-repo/semantics/publishedVersion
dc.type
info:eu-repo/semantics/conferenceObject
dc.type
info:ar-repo/semantics/documento de conferencia
dc.date.updated
2023-06-16T12:43:41Z
dc.journal.pagination
330-331
dc.journal.pais
Argentina
dc.journal.ciudad
¡
dc.description.fil
Fil: Saracho, Hayde. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.description.fil
Fil: Marcelino, Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.description.fil
Fil: Kurth, Daniel German. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/url/https://saib.org.ar/archivos/abstracts.pdf
dc.conicet.rol
Autor
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Autor
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Autor
dc.coverage
Nacional
dc.type.subtype
Reunión
dc.description.nombreEvento
LVIII Annual Meeting of the Argentine Society for Biochemistry and Molecular Biology Research
dc.date.evento
2022-11-07
dc.description.ciudadEvento
Mendoza
dc.description.paisEvento
Argentina
dc.type.publicacion
Book
dc.description.institucionOrganizadora
Sociedad Argentina De Investigación Bioquímica Y Biología Molecular
dc.source.libro
Resúmenes de Comunicaciones Orales y Posters de LVIII Annual Meeting of the Argentine Society for Biochemistry and Molecular Biology Research
dc.date.eventoHasta
2022-11-11
dc.type
Reunión
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