Artículo
The role of small GTPases in neuronal morphogenesis and polarity
González Billault, Christian; Muñoz Llancao, Pablo; Henriquez, Daniel R.; Wojnacki Fonseca, José Ignacio
; Conde, Cecilia Beatriz
; Martínez Cáceres, Alfredo Iván
Fecha de publicación:
07/2012
Editorial:
Wiley
Revista:
Cytoskeleton
ISSN:
1949-3584
e-ISSN:
1949-3592
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton support neuronal morphogenesis. Small RhoGTPases family members have emerged as crucial regulators of cytoskeletal dynamics. In this review we will comprehensively analyze findings that support the participation of RhoA, Rac, Cdc42, and TC10 in different neuronal morphogenetic events ranging from migration to synaptic plasticity. We will specifically address the contribution of these GTPases to support neuronal polarity and axonal elongation. © 2012 Wiley Periodicals, Inc.
Palabras clave:
CDC42
,
CYTOSKELETON DYNAMICS
,
NEURONAL POLARITY
,
RAC1
,
RHOA
,
TC10
Archivos asociados
Licencia
Identificadores
Colecciones
Articulos(INIMEC - CONICET)
Articulos de INSTITUTO DE INV. MEDICAS MERCEDES Y MARTIN FERREYRA
Articulos de INSTITUTO DE INV. MEDICAS MERCEDES Y MARTIN FERREYRA
Citación
González Billault, Christian; Muñoz Llancao, Pablo; Henriquez, Daniel R.; Wojnacki Fonseca, José Ignacio; Conde, Cecilia Beatriz; et al.; The role of small GTPases in neuronal morphogenesis and polarity; Wiley; Cytoskeleton; 69; 7; 7-2012; 464-485
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