Artículo
Sertaconazole antifungal profile determined by a microdilution method versus nine topical substances against dermatophyte fungi
Carrillo Muñoz, A. J.; Tur Tur, C.; Cárdenes, D.; Rojas, Florencia Dinorah
; Giusiano, Gustavo Emilio
![Icon](/themes/CONICETDigital/images/conicet.png)
![Icon](/themes/CONICETDigital/images/conicet.png)
Fecha de publicación:
09/2012
Editorial:
Karger
Revista:
Chemotherapy
ISSN:
0009-3157
Idioma:
Inglés
Tipo de recurso:
Artículo publicado
Clasificación temática:
Resumen
Antifungal activity and in vitro inhibition time for sertaconazole (STZ) and 9 other topical drugs, namely amorolfine, bifonazole, clotrimazole, econazole, ketoconazole, miconazole, oxiconazole, terbinafine, and tioconazole were determined against 124 clinical isolates of dermatophyte (12 species) fungi by the microdilution method in a liquid medium and the measurement of optical density. STZ's antifungal activity was not always affected by the tested dermatophyte genus, as was the case with the remaining antifungals. In vitro antifungal activity was at the same level for all the studied azole derivatives, but, in terms of partial inhibitory concentrations, STZ starts its in vitro inhibitory activity in a shorter time than the other tested substances, particularly in those incubation periods when the growth of the dermatophyte fungi was more developed.
Palabras clave:
DERMATOPHYTES
,
DERMATOPHYTOSIS
,
TOPICAL ANTIFUNGALS
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Colecciones
Articulos(CCT - NORDESTE)
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NORDESTE
Articulos de CTRO.CIENTIFICO TECNOL.CONICET - NORDESTE
Citación
Carrillo Muñoz, A. J.; Tur Tur, C.; Cárdenes, D.; Rojas, Florencia Dinorah; Giusiano, Gustavo Emilio; Sertaconazole antifungal profile determined by a microdilution method versus nine topical substances against dermatophyte fungi; Karger; Chemotherapy; 58; 5; 9-2012; 399-404
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