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dc.contributor.author
Pezzoni, Magdalena  
dc.contributor.author
De Troch, Marleen  
dc.contributor.author
Pizarro, Ramón Augusto  
dc.contributor.author
Costa, Cristina Susana  
dc.date.available
2023-05-09T17:24:36Z  
dc.date.issued
2022-07  
dc.identifier.citation
Pezzoni, Magdalena; De Troch, Marleen; Pizarro, Ramón Augusto; Costa, Cristina Susana; Homeophasic Adaptation in Response to UVA Radiation in Pseudomonas aeruginosa: Changes of Membrane Fatty Acid Composition and Induction of desA and desB Expression; Wiley Blackwell Publishing, Inc; Photochemistry and Photobiology; 98; 4; 7-2022; 886-893  
dc.identifier.issn
0031-8655  
dc.identifier.uri
http://hdl.handle.net/11336/196864  
dc.description.abstract
In bacteria, exposure to changes in environmental conditions can alter membrane fluidity, thereby affecting its essential functions in cell physiology. To adapt to these changes, bacteria maintain appropriate fluidity by varying the composition of the fatty acids of membrane phospholipids, a phenomenon known as homeophasic adaptation. In Pseudomonas aeruginosa, this response is achieved mainly by two mechanisms of fatty acid desaturation: the FabA–FabB and DesA–DesB systems. This study analyzed the effect of ultraviolet-A (UVA) radiation—the major fraction of solar UV radiation reaching the Earth's surface—on the homeophasic process. The prototypical strain PAO1 was grown under sublethal UVA doses or in the dark, and the profiles of membrane fatty acids were compared at early logarithmic, logarithmic and stationary growth phases. In the logarithmic growth phase, it was observed that growth under sublethal UVA doses induced the expression of the desaturase-encoding genes desA and desB and increased the proportion of unsaturated fatty acids; in addition, membrane fluidity could also increase, as suggested by the indices used as indicators of this parameter. The opposite effect was observed in the stationary growth phase. These results demonstrate the relevant role of UVA on the homeophasic response at transcriptional level.  
dc.format
application/pdf  
dc.language.iso
eng  
dc.publisher
Wiley Blackwell Publishing, Inc  
dc.rights
info:eu-repo/semantics/openAccess  
dc.rights.uri
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/  
dc.subject
RADIACIÓN ULTRAVIOLETA A  
dc.subject
HOMEOPHASIC ADAPTATION  
dc.subject
PSEUDOMONAS AERUGINOSA  
dc.subject
FATTY ACID  
dc.subject.classification
Otras Ciencias Naturales y Exactas  
dc.subject.classification
Otras Ciencias Naturales y Exactas  
dc.subject.classification
CIENCIAS NATURALES Y EXACTAS  
dc.title
Homeophasic Adaptation in Response to UVA Radiation in Pseudomonas aeruginosa: Changes of Membrane Fatty Acid Composition and Induction of desA and desB Expression  
dc.type
info:eu-repo/semantics/article  
dc.type
info:ar-repo/semantics/artículo  
dc.type
info:eu-repo/semantics/publishedVersion  
dc.date.updated
2023-05-09T11:48:15Z  
dc.journal.volume
98  
dc.journal.number
4  
dc.journal.pagination
886-893  
dc.journal.pais
Reino Unido  
dc.journal.ciudad
Londres  
dc.description.fil
Fil: Pezzoni, Magdalena. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina  
dc.description.fil
Fil: De Troch, Marleen. University of Ghent; Bélgica  
dc.description.fil
Fil: Pizarro, Ramón Augusto. Comisión Nacional de Energía Atómica; Argentina  
dc.description.fil
Fil: Costa, Cristina Susana. Comisión Nacional de Energía Atómica; Argentina  
dc.journal.title
Photochemistry and Photobiology  
dc.relation.alternativeid
info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/php.13548